Table 1.
Participants without LLVa, medians (IQR), n = 49 | Participants with LLV, medians (IQR), n = 33 | P valueb,c | |
Total number of visits (includes enrollment) | 9 (9 – 9) | 9 (8 – 9) | 0.090 |
Plasma HIV-1 RNA log10 (copies/ml) | 5.1 (4.8 – 5.6) | 5.7 (5.2 – 6.0) | <0.001 |
PBMC HIV DNA (copies/1 × 106 cells) | 1440 (500 – 2200) | 2600 (1070 – 4610) | 0.007 |
CD4+ lymphocytes (cells/μl) | 133 (43 – 213) | 123 (52 – 205) | 0.756 |
High sensitivity C-reactive protein (mg/l) | 2.9 (0.9 – 10.9) | 3.3 (1.2 – 4.9) | 0.647 |
Interleukin-6 (pg/ml)c | 3.5 (2.1 – 6.7) | 2.6 (1.8 – 4.3) | 0.080 |
Soluble CD14 (ng/ml)c | 3456 (3123 – 3867) | 3499 (2702 – 4412) | 0.945 |
Soluble CD25 (pg/ml)c | 2584 (1777 – 3811) | 2380 (1159 – 3190) | 0.166 |
Soluble CD163 (ng/ml)c | 2663 (1781 – 3639) | 3311 (2099 – 4446) | 0.105 |
Soluble tumor necrosis factor receptor-2 (pg/ml)c | 4720 (4336 – 5000) | 4600 (4264 – 5000) | 0.992 |
Soluble vascular cell adhesion molecule-1 (pg/ml)c | 1860 (1310–2539) | 2045 (1274–2952) | 0.754 |
ART, antiretroviral therapy; LLV, low-level viremia; PBMC, peripheral blood mononuclear cell.
aParticipants with all plasma HIV RNA less than 30 copies/ml during ART.
bCompared using a Wilcoxon two-sample test P < 0.05 (in bold) were noted.
cCytokines available from n = 44/49 without LLV and 33/33 with LLV.