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. 2018 Jul 2;32(11):1389–1401. doi: 10.1097/QAD.0000000000001824

Table 1.

Comparison of entry (preantiretroviral therapy) parameters between participants with versus without low-level viremias.

Participants without LLVa, medians (IQR), n = 49 Participants with LLV, medians (IQR), n = 33 P valueb,c
Total number of visits (includes enrollment) 9 (9 – 9) 9 (8 – 9) 0.090
Plasma HIV-1 RNA log10 (copies/ml) 5.1 (4.8 – 5.6) 5.7 (5.2 – 6.0) <0.001
PBMC HIV DNA (copies/1 × 106 cells) 1440 (500 – 2200) 2600 (1070 – 4610) 0.007
CD4+ lymphocytes (cells/μl) 133 (43 – 213) 123 (52 – 205) 0.756
High sensitivity C-reactive protein (mg/l) 2.9 (0.9 – 10.9) 3.3 (1.2 – 4.9) 0.647
Interleukin-6 (pg/ml)c 3.5 (2.1 – 6.7) 2.6 (1.8 – 4.3) 0.080
Soluble CD14 (ng/ml)c 3456 (3123 – 3867) 3499 (2702 – 4412) 0.945
Soluble CD25 (pg/ml)c 2584 (1777 – 3811) 2380 (1159 – 3190) 0.166
Soluble CD163 (ng/ml)c 2663 (1781 – 3639) 3311 (2099 – 4446) 0.105
Soluble tumor necrosis factor receptor-2 (pg/ml)c 4720 (4336 – 5000) 4600 (4264 – 5000) 0.992
Soluble vascular cell adhesion molecule-1 (pg/ml)c 1860 (1310–2539) 2045 (1274–2952) 0.754

ART, antiretroviral therapy; LLV, low-level viremia; PBMC, peripheral blood mononuclear cell.

aParticipants with all plasma HIV RNA less than 30 copies/ml during ART.

bCompared using a Wilcoxon two-sample test P < 0.05 (in bold) were noted.

cCytokines available from n = 44/49 without LLV and 33/33 with LLV.