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. 2018 Jul 10;8:10412. doi: 10.1038/s41598-018-28725-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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GABAergic spontaneous IPSCs. (A) Raster plots displaying all events in 1 min of recording from all patched cells. (B) Representative traces of spontaneous IPSCs with detected events marked (*) for Wistar (blue) and WAR (fucsia) cells. All events disappeared after addition of picrotoxin (20 µM) in the bath. (C) Histograms with the sum of all inter-event intervals (IEI; Bin width = 200 ms). (D) Cumulative fraction of events of IEIs. (E) Mean global frequency of IPSCs for each group of animals. (F) Histogram showing distribution of events by amplitude recorded during 1 min (Bin width = 20pA). (G) Cumulative fraction of amplitudes per group. (H) Mean amplitude of all detected IPSCs per group. **P < 0.01. N = 15 cells from 7 Wistars and N = 20 from 7 WARs.