Table 1.
Classification of subjects into Class A or B based on “slow oscillation”.
| Frequency range (Hz) | Pre | ISS01 | ISS02 | ISS03 | ISS01 vs. Pre | ISS02 vs. Pre | ISS03 vs. Pre | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SE | Mean | SE | Mean | SE | Mean | SE | t | p | t | p | t | p | ||
| Group A: B2-band response (+) | |||||||||||||||
| LF-band response (+) | |||||||||||||||
| Case 1 | |||||||||||||||
| B2 | 0.10–0.20 | 149.8 | 7.07 | 138.7 | 4.70 | 160.8 | 4.86 | 191.6 | 7.33 | 4.10 | 0.0005 | ||||
| LF-b | 0.01–0.05 | 1007.5 | 54.7 | 749.0 | 38.2 | 952.9 | 47.9 | 1235.2 | 57.1 | 2.88 | 0.0408 | ||||
| LF-c | 0.05–0.15 | 459.4 | 18.8 | 449.4 | 14.6 | 543.9 | 16.8 | 664.5 | 20.5 | 3.35 | 0.0085 | 7.37 | <0.0001 | ||
| HF-c | 0.15–0.50 | 135.9 | 6.9 | 102.1 | 3.4 | 109.1 | 3.0 | 138.3 | 3.8 | ||||||
| Case 2 | |||||||||||||||
| B2 | 0.10–0.20 | 216.7 | 8.75 | 346.3 | 9.00 | 273.2 | 8.41 | 341.9 | 10.33 | 10.32 | <0.0001 | 4.65 | <0.0001 | 9.25 | <0.0001 |
| LF-b | 0.01–0.05 | 1119.3 | 52.1 | 1370.5 | 53.6 | 797.7 | 33.8 | 1035.5 | 41.1 | 3.36 | 0.0084 | ||||
| LF-c | 0.05–0.15 | 641.9 | 22.2 | 1035.1 | 26.9 | 761.0 | 21.8 | 837.0 | 20.7 | 11.27 | <0.0001 | 3.83 | 0.0014 | 6.43 | <0.0001 |
| HF-c | 0.15–0.50 | 177.1 | 6.9 | 242.3 | 6.3 | 170.9 | 6.2 | 242.8 | 10.0 | 6.95 | <0.0001 | 5.41 | <0.0001 | ||
| Case 3 | |||||||||||||||
| B2 | 0.10–0.20 | 25.5 | 0.90 | 22.1 | 0.80 | 33.6 | 1.28 | 30.4 | 1.04 | 5.20 | <0.0001 | 3.60 | 0.0036 | ||
| LF-b | 0.01–0.05 | 392.9 | 20.0 | 443.4 | 22.5 | 488.8 | 24.9 | 526.6 | 34.8 | 3.00 | 0.0277 | 3.34 | 0.0092 | ||
| LF-c | 0.05–0.15 | 120.0 | 3.8 | 106.9 | 3.3 | 161.4 | 5.0 | 146.4 | 6.3 | 6.59 | <0.0001 | 3.60 | 0.0037 | ||
| HF-c | 0.15–0.50 | 42.8 | 1.0 | 24.0 | 0.6 | 34.1 | 1.0 | 35.2 | 1.1 | ||||||
| Case 4 | |||||||||||||||
| B2 | 0.10–0.20 | 121.0 | 5.12 | 147.2 | 5.77 | 150.0 | 5.43 | 172.7 | 6.28 | 3.39 | 0.0076 | 3.88 | 0.0011 | 6.37 | <0.0001 |
| LF-b | 0.01–0.05 | 880.7 | 30.8 | 812.7 | 36.2 | 915.3 | 43.4 | 1143.9 | 66.9 | 3.57 | 0.0040 | ||||
| LF-c | 0.05–0.15 | 571.0 | 23.7 | 538.6 | 21.0 | 543.6 | 19.1 | 595.8 | 21.2 | ||||||
| HF-c | 0.15–0.50 | 73.6 | 2.3 | 97.9 | 3.5 | 89.3 | 3.8 | 161.3 | 5.4 | 5.79 | <0.0001 | 3.56 | 0.0041 | 15.03 | <0.0001 |
| Group B: B2-band response (−) | |||||||||||||||
| LF-band response (+) | |||||||||||||||
| Case 5 | |||||||||||||||
| B2 | 0.10–0.20 | 169.6 | 5.98 | 93.9 | 3.03 | 84.5 | 2.50 | 96.8 | 3.59 | ||||||
| LF-b | 0.01–0.05 | 640.8 | 26.2 | 1077.1 | 69.9 | 1121.6 | 72.0 | 937.8 | 64.6 | 5.85 | <0.0001 | 6.23 | <0.0001 | 4.26 | 0.0003 |
| LF-c | 0.05–0.15 | 488.2 | 15.1 | 295.4 | 10.0 | 280.1 | 8.6 | 266.3 | 9.4 | ||||||
| HF-c | 0.15–0.50 | 120.5 | 3.1 | 94.3 | 3.2 | 77.5 | 2.1 | 214.4 | 10.4 | 8.64 | <0.0001 | ||||
| Case 6 | |||||||||||||||
| B2 | 0.10–0.20 | 132.1 | 4.74 | 103.3 | 3.61 | 107.6 | 2.88 | 113.0 | 3.29 | ||||||
| LF-b | 0.01–0.05 | 715.3 | 40.5 | 715.4 | 32.9 | 787.1 | 38.0 | 881.3 | 39.3 | 2.94 | 0.0335 | ||||
| LF-c | 0.05–0.15 | 583.0 | 20.7 | 448.5 | 13.9 | 407.2 | 10.6 | 482.7 | 16.7 | ||||||
| HF-c | 0.15–0.50 | 59.9 | 2.0 | 60.7 | 1.7 | 79.6 | 1.9 | 75.4 | 1.8 | 7.11 | <0.0001 | 5.64 | <0.0001 | ||
| LF-band response (−) | |||||||||||||||
| Case 7 | |||||||||||||||
| B2 | 0.10–0.20 | 172.9 | 7.36 | 152.9 | 4.81 | 107.2 | 3.90 | 130.9 | 4.02 | ||||||
| LF-b | 0.01–0.05 | 2661.7 | 159.3 | 2251.2 | 143.9 | 1420.1 | 84.6 | 2305.5 | 133.4 | ||||||
| LF-c | 0.05–0.15 | 683.7 | 22.9 | 617.2 | 19.6 | 467.7 | 16.6 | 557.8 | 19.6 | ||||||
| HF-c | 0.15–0.50 | 174.2 | 5.0 | 165.0 | 3.4 | 107.9 | 2.6 | 128.3 | 2.8 | ||||||
| Case 8 | |||||||||||||||
| B2 | 0.10–0.20 | 355.5 | 12.29 | 254.9 | 8.61 | 327.6 | 10.06 | 325.2 | 11.96 | ||||||
| LF-b | 0.01–0.05 | 2907.3 | 188.9 | 2137.7 | 129.9 | 2165.7 | 131.8 | 2719.0 | 194.6 | ||||||
| LF-c | 0.05–0.15 | 1110.4 | 38.1 | 878.4 | 34.2 | 1025.4 | 34.7 | 997.1 | 38.2 | ||||||
| HF-c | 0.15–0.50 | 213.8 | 8.2 | 156.9 | 4.8 | 194.1 | 5.4 | 213.3 | 8.0 | ||||||
B2-band (B2-b), HRV-SFO; LF-band: HRV-VSFO; LF-c: HRV LF-component; HF-c: HRV HF-component.
N between 260 and 287; t: Student t; p: P-value (Sidak correction).