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Different CARMA/caspase-recruitment domains (CARDs) connect to B-cell lymphoma/leukemia 10 (BCL10)-mucosa-associated lymphoid tissue (MALT)1 in response to distinct upstream stimuli BCL10/MALT1 complex recruitment to different CARMA/CARD proteins is dependent on activation of various receptor types forming distinct CBM complexes. All signaling pathways converge upon formation of CBM complexes leading to IκB kinase/NF-κB and JNK activation similarly.
