Table 1.

Correlation results between full length αII-spectrin or SBDP protein levels in CSF and tissues specified by brain region and time point.

	24 h		3 days		7 days		1 month		3 months
	r	p-value	r	p-value	r	p-value	r	p-value	r	p-value
αII-Spectrin
FCX	−0.338	0.078	−0.417	0.096	0.141	0.483	0.273	0.153	−0.338	0.079
STM	−0.315	0.102	−0.172	0.509	−0.082	0.691	−0.145	0.454	−0.221	0.249
HC	−0.017	0.931	−0.256	0.322	0.049	0.808	−0.169	0.380	−0.030	0.881
RMB	−0.229	0.251	0.470	0.057	0.075	0.717	0.168	0.384	0.014	0.942
SBDP-145/150
FCX	0.287	0.139	0.295	0.206	0.777	< 0.0001****	−0.065	0.738	0.398	0.066
STM	0.582	0.001**	0.880	< 0.0001****	0.507	0.008**	0.124	0.523	0.251	0.249
HC	0.095	0.631	0.498	0.030*	−0.188	0.348	−0.219	0.254	−0.016	0.943
RMB	0.655	0.000***	0.918	< 0.0001****	0.559	0.002**	0.081	0.678	−0.179	0.413
SBDP-120
FCX	−0.083	0.673	−0.094	0.693	0.560	0.002**	−0.188	0.358	−0.070	0.733
STM	0.155	0.450	0.105	0.660	−0.059	0.776	−0.299	0.138	0.247	0.235
HC	−0.240	0.229	0.030	0.902	−0.361	0.064	0.059	0.775	−0.200	0.317
RMB	−0.359	0.066	−0.241	0.307	0.181	0.365	−0.047	0.821	−0.073	0.731

Pearson r correlation analyses were performed between levels of αII-spectrin or SBDPs in CSF and brain tissues by region and time point post injury. Protein levels were determined by Western blot at each time point post injury and were expressed as normalized values for CSF markers and as a percent sham for tissue markers for analysis. Sham, Probe, and PBBI injured rats were all included for analysis. Significant correlations are marked with

^*(p < 0.05),

^**(p < 0.01),

^***(p < 0.001), or

^****(p ≤ 0.0001).

CSF, cerebrospinal fluid; FCX, frontal cortex; STM, striatum; HC, hippocampus; RMB, residual midbrain.