Table 2.
Results of the DATE–apraxia assessment
| HC (n = 34) | AD (n = 27) | bvFTD (n = 31) | svPPA (n = 21) | nfPPA (n = 14) | Group differences∗ | |
|---|---|---|---|---|---|---|
| DATE total score, max. 15 | 13.06 ± 1.07 | 10.28 ± 2.22 | 9.86 ± 2.65 | 8.94 ± 2.41 | 6.59 ± 3.44 | HC > (AD, bvFTD, svPPA, nfPPA) (AD, bvFTD) > nfPPA |
| Scales | ||||||
| DATE 1 limb apraxia, max. 6 | 4.61 ± 0.81 | 3.12 ± 1.09 | 4.15 ± 1.1 | 3.08 ± 1.5 | 2.82 ± 1.64 | (HC, bvFTD) > (AD, svPPA, nfPPA) |
| DATE 2 face apraxia, max. 9 | 8.44 ± 0.83 | 7.51 ± 1.48 | 5.7 ± 1.97 | 5.86 ± 1.51 | 3.76 ± 2.19 | HC > (AD, bvFTD, svPPA, nfPPA) AD > (bvFTD, svPPA, nfPPA), svPPA > nfPPA |
| Subscales | ||||||
| Limb imitation, max. 3 | 2.13 ± 0.36 | 1.19 ± 0.59 | 1.65 ± 0.61 | 1.41 ± 0.72 | 1.21 ± 0.73 | HC > (AD, bvFTD, svPPA, nfPPA) AD < bvFTD |
| Object pantomime, max. 3 | 2.49 ± 0.68 | 1.88 ± 0.92 | 2.52 ± 0.72 | 1.69 ± 1.07 | 1.46 ± 1.22 | (HC, bvFTD) > svPPA |
| Buccofacial emblems, max. 3 | 2.82 ± 0.49 | 2.38 ± 0.96 | 1.98 ± 1.06 | 1.45 ± 1.12 | 1.18 ± 1.20 | HC > (bvFTD, svPPA, nfPPA) AD > (svPPA, nfPPA) |
| Pseudowords, max. 3 | 2.81 ± 0.52 | 2.44 ± 0.86 | 2.02 ± 0.91 | 2.33 ± 0.83 | 0.88 ± 0.96 | HC > (bvFTD, nfPPA) (AD, bvFTD, svPPA) > nfPPA |
| Face imitation, max. 3 | 2.81 ± 0.28 | 2.23 ± 0.63 | 1.77 ± 0.76 | 2.14 ± 0.67 | 1.6 ± 0.74 | HC > (AD, bvFTD, svPPA, nfPPA) |
Abbreviations: HC, healthy controls; AD, Alzheimer's disease; bvFTD, behavioral variant of frontotemporal dementia; svPPA, semantic variant of primary-progressive aphasia; nfPPA, nonfluent primary-progressive aphasia; DATE, Dementia Apraxia Test; ANOVA, analysis of variance.
NOTE. Results are expressed as mean ± SD.
∗
Significant differences (P < .05) between groups by ANOVAs and post hoc comparisons (Games-Howell Tests).