Table 2. Indications and contraindications for endovascular treatment of PAVM.
Indications for endovascular therapy |
PAVM with a feeding artery diameter (FAD) ≥2 mm, and technically feasible |
Symptomatic PAVM regardless of size |
Atypical but likely PAVM on cross sectional imaging and suggestive symptoms |
Relative contraindications (possible alternative) |
Asymptomatic PAVM with feeding artery diameter <2 mm (consider clinical and CT follow up) |
PAVM that is not accessible/feasible for endovascular therapy (consider surgical resection) |
Diffuse type PAVM (surgery/transplant) |
Severe pulmonary hypertension (consider performing the procedure under local anesthesia only; decrease the rate and volume of injected contrast material; use hand injection; occlude only a few PAVMs during each treatment session) |
Severe coagulopathy (correct underlying coagulopathy) |
Renal failure (consider nephrology consult) |
Allergy to iodinated contrast material (consider premedication) |
Early pregnancy (PAVM can be treated in the second and third trimesters as pregnancy typically exacerbates and complicates PAVM presentation) |
Asymptomatic PAVM in children |
Left bundle branch block (consider temporary pacing) |
PAVM, pulmonary arteriovenous malformations.