Table 1.
Characteristics of 225 786 women who underwent assisted reproduction in Great Britain, 1991-2010
| Characteristic | Total cohort (n=255 786) | Women who developed ovarian, breast, and corpus uteri cancer (n=3155) | Women who did not develop ovarian, breast, and corpus uteri cancer (n=252 631) |
|---|---|---|---|
| Age at first treatment (years; mean (SD)) | 34.5 (4.8) | 36.3 (4.7) | 34.5 (4.8) |
| Age at first treatment (No (%)) | |||
| <25 years | 5671 (2) | 20 (1) | 5651 (2) |
| 25-29 years | 39 932 (16) | 259 (8) | 39 673 (16) |
| 30-34 years | 92 788 (36) | 961 (31) | 91 827 (36) |
| 35-39 years | 85 868 (34) | 1244 (39) | 84 624 (34) |
| 40-44 years | 28 174 (11) | 563 (18) | 27 611 (11) |
| ≥45 years | 3353 (1) | 108 (3) | 3245 (1) |
| Cause of infertility (No (%)) | |||
| Any female factor | 111 658 (44) | 1626 (52) | 110 032 (44) |
| Male factor only | 84 871 (33) | 915 (29) | 83 956 (33) |
| Unexplained | 47 757 (19) | 474 (15) | 47 283 (19) |
| Unrecorded | 11 500 (5) | 140 (4) | 11 360 (5) |
| History of endometriosis (No (%)) | 18 630 (7) | 281 (9) | 18 349 (7) |
| History of tubal disease (No (%)) | 66 370 (26) | 1045 (33) | 65 325 (26) |
| History of ovulatory disorder (No (%)) | 36 016 (14) | 451 (14) | 35 565 (14) |
| Duration of infertility reported at completion of last cycle (years; mean (SD)) | 4.9 (3.3) | 5.6 (3.9) | 4.8 (3.3) |
| No of stimulated cycles (mean (SD)) | 1.8 (1.2) | 1.8 (1.3) | 1.8 (1.2) |
| No of live births at completion of last cycle (mean (SD)) | 0.6 (0.7) | 0.6 (0.7) | 0.6 (0.7) |
| No of live births at completion of last cycle (No (%)) | |||
| 0 | 129 217 (51) | 1775 (56) | 127 442 (50) |
| 1 | 96 839 (38) | 1011 (32) | 95 828 (38) |
| ≥2 | 29 645 (12) | 368 (12) | 29 277 (11) |
| Unrecorded | 85 (0) | 1 (0) | 84 (0) |
| Any multiple birth recorded at completion of last cycle (No (%)) | 29 366 (11) | 304 (10) | 29 062 (12) |
SD=standard deviation.