Table 2.
Relative and absolute excess risks of cancers of breast, ovary, and corpus uteri among 225 786 women who underwent assisted reproduction in Great Britain, 1991-2010, including and excluding the first year after the start of treatment
Type of cancer | Follow-up (No of person years) | No of observed cancers | No of expected cancers | Standardised incidence ratio (95% CI) | Absolute excess risk (95% CI) per 100 000 person years at risk |
---|---|---|---|---|---|
Including first year of follow-up | |||||
Breast* | 2 257 789 | 2578 | 2641.2 | 0.98 (0.94 to 1.01) | −2.8 (−7.1 to 1.8) |
Corpus uteri† | 2 257 789 | 164 | 146.9 | 1.12 (0.95 to 1.30) | 0.8 (−0.3 to 2.0) |
Ovary‡ | 2 257 789 | 405 | 291.82 | 1.39 (1.26 to 1.53) | 5.0 (3.3 to 6.9) |
Excluding first year of follow-up | |||||
Breast* | 2 004 121 | 2384 | 2501.6 | 0.95 (0.92 to 0.99) | −5.9 (−10.6 to −1.0) |
Corpus uteri† | 2 004 121 | 157 | 141.79 | 1.11 (0.94 to 1.30) | 0.8 (−0.4 to 2.1) |
Ovary‡ | 2 004 121 | 356 | 271.9 | 1.31 (1.18 to 1.45) | 4.2 (2.44 to 6.10) |
Breast cancer=ICD-9 codes 1740-1749, 2330, and 2383; ICD-10 codes C500-C509, D050-D059, and D486.
Corpus uteri cancer=ICD-9 codes 1820-1828 and ICD-10 code C54.
Ovarian cancer=ICD-9 codes 1830-1839 and 2362; ICD-10 codes C56, C570-C574, C481, C482, and D391.