Table 1.

CRBSI adapted criteria.

Definite CRBSI - criteria require one of the following:  • Bloodstream infection (BSI) occurring 48 h before or after catheter removal AND differential period of CVC culture vs. peripheral blood culture positivity of > 2 h  • BSI occurring 48 h before or after catheter removal AND positive culture with the same microorganism from pus from insertion site  • BSI semi-quantitative CVC culture > 15 CFU and clinical signs improve within 48 h after catheter removal Probable CRBSI  • BSI occurring 48 h before or after catheter removal which does not fulfil the definitions above but there is no alternative source of infection. This needs agreement between microbiologist and the patient’s clinical team BSI defined as: One positive blood culture for a recognised pathogen or patient has at least one of the following signs or symptoms: fever (> 38 °C), chills or hypotension AND two positive blood cultures for a common skin contaminant (from two separate blood samples, usually within 48 h) Skin contaminants = coagulase-negative staphylococci, Micrococcus sp., Propionibacterium acnes, Bacillus sp., Corynebacterium sp.

Adapted from European Centre for Disease Prevention and Control (2016).