Figure 2. Brain control of energy balance and effects of low or high energy intake on partitioning of endogenous and exogenous energy to and from fat mass (FM) and fat free mass (FFM).

FFM and FM both exert feedback controls on different levels of the brain control systems of energy balance. It is assumed that FFM is the major determinant of energy balance. See text for further details. The right part of the figure (i.e. the partitioning model) is based on the original work of Jonathan Wells (see 83).