Skip to main content
. 2018 Jun 27;7:296. Originally published 2018 Mar 8. [Version 2] doi: 10.12688/f1000research.14239.2

Figure 3. Antigen-specific interferon gamma response varies in splenocytes of ML high and ML low mouse strains.

Figure 3.

Splenocytes were isolated from BCG-immunised or control mice at the time of Mtb challenge (6 weeks after immunisation), and restimulated with PPD. The number of IFNγ producing cells were enumerated using an ELISPOT assay (presented as spot forming units [SFU] per 10e6 cells). Non-specific background measured in unstimulated duplicate wells was removed. Data sets are presented in order of decreasing protection. Each symbol represents one animal. p values were determined by using one-way ANOVA and Dunn’s post test for multiple comparisons. Error bars represent the median and interquartile range. Multiplicity adjusted p values are reported. p<0.05 was considered statistically significant.