Table 1. Spectrum and instruments of investigation of the birth cohorts GINIplus and LISAplus.
| Age (years) | ||||||||
| 0 | 1 | 2 | (3) | 4 | 6 | 10 | 15 | |
| Questionnaires | ||||||||
| Diseases and symptoms (allergies) | X | X | X | X | X | X | X | X |
| Social factors | X | X | X | X | X | |||
| Vaccinations | X | X | X | |||||
| Exposure to noxious substances | ||||||||
| Passive smoking | X | X | X | X | X | X | X | X |
| Indoors | X | X | X | X | X | X | X | X |
| Outdoors | X | X | X | X | ||||
| Health-related behavior | ||||||||
| Physical activities Accelerometry |
X | X | X X | |||||
| Nutrition | ||||||||
| Breast-feeding | X | X | ||||||
| List of items | X | X | X | ´X | ||||
| FFQ | X | X | ||||||
| Mental deviations | X | X | ||||||
| SDQ | X | X | ||||||
| Depression | X | |||||||
| Kidscreen | X | |||||||
| Medical investigation | ||||||||
| Skin | (X) | (X) | (X) | (X) | ||||
| Lungs | X | (X) | X | |||||
| FENO | X | X | ||||||
| Anthropometry | X | X | X | X | ||||
| BIA | X | |||||||
| Blood pressure | X | X | ||||||
| Dental health | (X) | (X) | ||||||
| Blood analyses | ||||||||
| Total IgE | (X) | (X) | (X) | X | X | X | ||
| Specific IgE | (X) | (X) | (X) | X | X | X | ||
| IgA | X | (X) | ||||||
| Viral AB | (X) | |||||||
| Vaccination AB | (X) | X | X | |||||
| T-cell immunity | (X) | (X) | (X) | (X) | ||||
| Lipids | X | X | ||||||
| Inflammation markers | X | X | ||||||
| HOMA (fasted blood) | (X) | (X) | ||||||
| Fatty acids | (X) | (X) | (X) | (X) | ||||
| Genetic analyses (allergies and determinants) |
X | |||||||
| Exposure | ||||||||
| Air pollutants (LUR model) | X | X | X | X | X | |||
| Noise | X | X | X | X | X | |||
| Use of health service / costs | X | X | ||||||
(X): only in partial samples; FFQ: Food Frequency Questionnaire; SDQ: Strength and Difficulties Questionnaire; FENO: Fractionated Exhaled NO; BIA: bioelectric impedance analysis; AB: antibody; HOMA index: Homeostasis Model Assessment; LUR: Land Use Regression Model.