Table 3. Incidence and characteristics of immediate-type reactions to platinum-based chemotherapeutic drugs. Modified from [24, 31].

Drug	Incidence	Characteristics
Cisplatin	5 – 20%	Within minutes during infusion Mostly during the 4th – 8th cycle Risk increased with concomitant radiation
Carboplatin	1 – 44%	Within minutes to days after infusion Very rarely during the first 5 cycles > 35% after 5th cycle
Oxaliplatin	10 – 18.9%	Within minutes or hours Mostly after 5th cycle Mostly severe anaphylactic reactions