Skip to main content
. 2018 Jan;70(1):68–141. doi: 10.1124/pr.117.013896

TABLE 1 .

Wnts and cardiovascular development

Gene Pathway Role Reference
WNT1 β-catenin mediated Cardiac neural crest cell development and outflow tract development Brault et al. (2001)
WNT2B non-β-catenin mediated Inhibition of cardiac progenitor cells Wang et al. (2007)
WNT3A β-catenin mediated Mesoderm formation Liu et al. (1999)
Inhibition of cardiac progenitor cells Marvin et al. (2001)
WNT5A non-β-catenin mediated Cardiomyocyte differentiation and outflow tract septation Schleiffarth et al. (2007)
WNT7A non-β-catenin mediated Conduction system development Bond et al. (2003)
WNT9B β-catenin mediated Epicardium development and coronary artery formation Zamora et al. (2007)
WNT11 non-β-catenin mediated Cardiomyocyte differentiation Pandur et al. (2002)
Outflow tract septation Zhou et al. (2007)
Conduction system development Bond et al. (2003)