Table III.
SF-36, HADS-D, HADS-A and MAF scores of pSS patients according to disease activity
| Variable | ESSDAI | ESSPRI | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| < 5 (n = 49) | 5–13 (n = 45) | ≥ 14 (n = 11) | P-value | P-value1 | P-value2 | P-value3 | < 5 (n = 55) | ≥ 5 (n = 50) | P-value | |
| PF | 47.35 ±6.59 | 43.66 ±5.77 | 39.71 ±5.87 | < 0.001 | < 0.001 | < 0.001 | 0.064 | 46.06 ±5.44 | 42.96 ±7.80 | 0.015 |
| RP | 46.87 ±8.53 | 41.26 ±8.23 | 42.08 ±6.86 | < 0.001 | < 0.001 | 0.006 | 0.671 | 46.21 ±6.62 | 40.20 ±10.01 | < 0.001 |
| BP | 46.95 ±7.33 | 44.10 ±7.73 | 38.78 ±8.54 | < 0.001 | 0.031 | 0.002 | 0.031 | 47.74 ±5.98 | 40.14 ±8.60 | 0.005 |
| GH | 46.66 ±8.05 | 41.69 ±7.47 | 38.55 ±3.83 | < 0.001 | < 0.001 | < 0.001 | 0.042 | 46.76 ±6.43 | 38.56 ±7.55 | < 0.001 |
| VT | 49.02 ±5.35 | 46.82 ±7.00 | 43.74 ±6.41 | 0.004 | 0.026 | 0.002 | 0.142 | 49.29 ±4.59 | 44.58 ±7.73 | < 0.001 |
| SF | 43.96 ±8.35 | 41.14 ±8.70 | 31.56 ±6.57 | < 0.001 | 0.047 | < 0.001 | 0.001 | 42.99 ±7.17 | 38.65 ±11.00 | 0.663 |
| RE | 44.62 ±10.29 | 37.84 ±9.49 | 31.40 ±9.05 | < 0.001 | < 0.001 | < 0.001 | 0.057 | 42.22 ±8.97 | 36.86 ±12.38 | 0.014 |
| MH | 39.31 ±7.83 | 37.89 ±6.30 | 36.03 ±3.65 | 0.135 | 0.225 | 0.056 | 0.284 | 39.07 ±6.11 | 37.12 ±7.77 | 0.289 |
| PCS | 48.44 ±6.71 | 44.10 ±6.46 | 41.98 ±5.17 | < 0.001 | < 0.001 | < 0.001 | 0.026 | 48.87 ±4.33 | 41.02 ±7.34 | < 0.001 |
| MCS | 42.29 ±5.95 | 39.43 ±6.56 | 33.68 ±5.36 | < 0.001 | 0.002 | < 0.001 | 0.003 | 41.16 ±4.88 | 38.30 ±8.53 | 0.002 |
| HADS-A | 7.22 ±3.70 | 8.11 ±3.82 | 8.00 ±2.72 | 0.365 | 0.215 | 0.303 | 0.819 | 6.22 ±2.23 | 9.30 ±4.23 | < 0.001 |
| HADS-D | 6.61 ±3.10 | 6.84 ±2.66 | 7.09 ±2.51 | 0.777 | 0.600 | 0.563 | 0.721 | 6.04 ±2.36 | 7.56 ±3.12 | 0.001 |
| MAF | 19.63 ±8.99 | 23.85 ±9.20 | 22.39 ±7.80 | 0.067 | 0.024 | 0.248 | 0.695 | 16.89 ±6.70 | 27.05 ±8.47 | < 0.001 |
Values are presented as mean ± SD. ESSDAI – EULAR Sjögren’s syndrome disease activity index, ESSPRI – EULAR Sjögren’s syndrome patient reported index, EULAR – European League Against Rheumatism, MAF – Multidimensional Assessment of Fatigue, HADS-A – Hospital Anxiety and Depression Scale-anxiety, HADS-D – Hospital Anxiety and Depression Scale-depression, PF – physical functioning, RP – role-physical, BP – bodily pain, GH – general health, VT – vitality, SF – social functioning, RE – role-emotional, MH – mental health, PCS – physical component summary scores, MCS – mental component summary scores. Bold values indicate statistically significant differences. P-value1 – statistically significant difference between low disease activity and moderate disease activity, p-value2 – statistically significant difference between low disease activity and high disease activity, p-value3 – statistically significant difference between moderate disease activity and high disease activity.