Table 2.
Treatment related toxicities of RT alone and CRT groups.
| Toxicities | RT alone (n=97) | CRT(n=165) | P-value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Grade 0–1 | Grade 2 | Grade 3 | Grade 4 | Grade 0–1 | Grade 2 | Grade 3 | Grade 4 | ||
| <60 Gy | |||||||||
| Radiation esophagitis | 13 | 2 | 0 | 0 | 20 | 4 | 0 | 0 | 0.436 |
| Radiation pneumonia | 15 | 0 | 0 | 0 | 23 | 1 | 0 | 0 | 0.546 |
| Leukopenia | 14 | 1 | 0 | 0 | 14 | 6 | 4 | 0 | 0.006 |
| Thrombocytopenia | 15 | 0 | 0 | 0 | 22 | 2 | 0 | 0 | 0.345 |
| 60–65 Gy | |||||||||
| Radiation esophagitis | 26 | 4 | 1 | 0 | 57 | 12 | 2 | 0 | 0.515 |
| Radiation pneumonia | 29 | 1 | 1 | 0 | 65 | 5 | 1 | 0 | 0.680 |
| Leukopenia | 24 | 5 | 2 | 0 | 39 | 17 | 14 | 1 | 0.014 |
| Thrombocytopenia | 28 | 1 | 2 | 0 | 65 | 4 | 2 | 0 | 0.503 |
| >65 Gy | |||||||||
| Radiation esophagitis | 42 | 8 | 1 | 0 | 44 | 21 | 4 | 1 | 0.019 |
| Radiation pneumonia | 45 | 4 | 2 | 0 | 57 | 8 | 4 | 1 | 0.167 |
| Leukopenia | 36 | 11 | 3 | 1 | 32 | 25 | 12 | 1 | 0.001 |
| Thrombocytopenia | 49 | 2 | 0 | 0 | 61 | 6 | 3 | 0 | 0.192 |
RT – radiotherapy; CRT – concurrent chemoradiotherapy.