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. 2018 Jun 27;2018:1031367. doi: 10.1155/2018/1031367

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Copyright © 2018 Meiping Guan et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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TGF-β1-induced EMT reversed by siEgr-1 in NRK-52E cells. NRK-52E cells were transfected by siEgr-1 before TGF-β1 treatment. (a, b) The mRNA (a) and protein (b) expressions of Egr-1. (c–e) The mRNA expressions of E-cadherin, α-SMA, and FN. (f) The protein expression of Egr-1. (g–j) The protein expressions of E-cadherin, α-SMA, and FN. Values are shown as mean ± SD. n = 3 for each group. ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001 versus NC group. ^#p < 0.05 and ^##p < 0.01 versus (NC + TGF-β1) group.