Fig. 5. (A) Automated SABRE flow system that includes: (1) electrolysis cell, (2) Bruker p-H2 conversion unit, (3a) PTF solenoid coil, (3b) mixing chamber, (4) Bruker polarizer control unit, and (5) 43 MHz (1 T) Magritek Spinsolve Carbon NMR spectrometer. (B) 1H NMR spectra of 52 mM 4-methylpyridine with 5.2 mM catalyst in methanol-d4 acquired with (top) thermal polarization, (middle) SABRE hyperpolarization using the automated flow system, (bottom) SABRE hyperpolarization using manual shaking. Both SABRE spectra were acquired with a PTF ∼63 G. (C) Variability between repeated SABRE hyperpolarization experiments where the sample is repolarized between each acquisition. (D) Data from (A) normalized to the enhancement factor of the ortho resonance.
