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. 2018 Jun 6;4(6):e00642. doi: 10.1016/j.heliyon.2018.e00642

Table 2.

86 altered genes.

Symbol Entrez Gene Name Location Type(s)
1 ASB2 ankyrin repeat and SOCS box containing 2 Nucleus transcription regulator
2 ASB9 ankyrin repeat and SOCS box containing 9 Nucleus transcription regulator
3 DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 Nucleus enzyme
4 DEPDC1 DEP domain containing 1 Nucleus transcription regulator
5 DHRS2 dehydrogenase/reductase (SDR family) member 2 Nucleus enzyme
6 EBNA1BP2 EBNA1 binding protein 2 Nucleus other
7 GINS2 GINS complex subunit 2 (Psf2 homolog) Nucleus other
8 HIST1H1A histone cluster 1, H1a Nucleus other
9 HIST1H2AI histone cluster 1, H2ai Nucleus other
10 HIST1H2BC histone cluster 1, H2bc Nucleus other
11 HIST1H2BL histone cluster 1, H2bl Nucleus other
12 HIST1H3J histone cluster 1, H3j Nucleus other
13 HIST2H2AB histone cluster 2, H2ab Nucleus other
14 HIST2H2BF histone cluster 2, H2bf Nucleus other
15 HIST3H2BB histone cluster 3, H2bb Nucleus other
16 MCM2 minichromosome maintenance complex component 2 Nucleus enzyme
17 POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) Nucleus enzyme
18 RANBP1 RAN binding protein 1 Nucleus other
19 S100A2 S100 calcium binding protein A2 Nucleus other
20 TERT telomerase reverse transcriptase Nucleus enzyme
21 APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B Cytoplasm enzyme
22 BSPRY B-box and SPRY domain containing Cytoplasm other
23 CAMK1 calcium/calmodulin-dependent protein kinase I Cytoplasm kinase
24 CCNB1 cyclin B1 Cytoplasm kinase
25 DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides Cytoplasm other
26 GAD1 glutamate decarboxylase 1 (brain, 67kDa) Cytoplasm enzyme
27 GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 Cytoplasm enzyme
28 GLDC glycine dehydrogenase (decarboxylating) Cytoplasm enzyme
29 KLK1 kallikrein 1 Cytoplasm peptidase
30 MB myoglobin Cytoplasm transporter
31 NCF2 neutrophil cytosolic factor 2 Cytoplasm enzyme
32 NME1 NME/NM23 nucleoside diphosphate kinase 1 Cytoplasm kinase
33 ODF1 outer dense fiber of sperm tails 1 Cytoplasm other
34 PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase Cytoplasm enzyme
35 PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Cytoplasm enzyme
36 PTPN3 protein tyrosine phosphatase, non-receptor type 3 Cytoplasm phosphatase
37 SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 Cytoplasm other
38 STON2 stonin 2 Cytoplasm other
39 TPRG1 tumor protein p63 regulated 1 Cytoplasm other
40 ART3 ADP-ribosyltransferase 3 Plasma Membrane enzyme
41 CCR2 chemokine (C-C motif) receptor 2 Plasma Membrane G-protein coupled receptor
42 CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) Plasma Membrane transmembrane receptor
43 CLECL1 C-type lectin-like 1 Plasma Membrane other
44 CPNE5 copine V Plasma Membrane other
45 ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 Plasma Membrane enzyme
46 GAP43 growth associated protein 43 Plasma Membrane other
47 GJB2 gap junction protein, beta 2, 26kDa Plasma Membrane transporter
48 GNA14 guanine nucleotide binding protein (G protein), alpha 14 Plasma Membrane enzyme
49 HCAR1 hydroxycarboxylic acid receptor 1 Plasma Membrane G-protein coupled receptor
50 IGHM immunoglobulin heavy constant mu Plasma Membrane transmembrane receptor
51 IL17RB interleukin 17 receptor B Plasma Membrane transmembrane receptor
52 IL23R interleukin 23 receptor Plasma Membrane transmembrane receptor
53 MYO3B myosin IIIB Plasma Membrane kinase
54 NINJ2 ninjurin 2 Plasma Membrane other
55 TNFRSF8 tumor necrosis factor receptor superfamily, member 8 Plasma Membrane transmembrane receptor
56 CGREF1 cell growth regulator with EF-hand domain 1 Extracellular Space other
57 EBI3 Epstein-Barr virus induced 3 Extracellular Space cytokine
58 FBLN5 fibulin 5 Extracellular Space other
59 IFNG interferon, gamma Extracellular Space cytokine
60 IL17A interleukin 17A Extracellular Space cytokine
61 IL17F interleukin 17F Extracellular Space cytokine
62 IL5 interleukin 5 Extracellular Space cytokine
63 IL9 interleukin 9 Extracellular Space cytokine
64 LTA lymphotoxin alpha Extracellular Space cytokine
65 NAPSA napsin A aspartic peptidase Extracellular Space peptidase
66 PRG4 proteoglycan 4 Extracellular Space other
67 TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 Extracellular Space cytokine
68 C4orf26 chromosome 4 open reading frame 26 Other other
69 CDC20P1 cell division cycle 20 pseudogene 1 Other other
70 CKS2 CDC28 protein kinase regulatory subunit 2 Other kinase
71 COX17P1 COX17 cytochrome c oxidase copper chaperone pseudogene 1 Other other
72 HMSD histocompatibility (minor) serpin domain containing Other other
73 HPDL 4-hydroxyphenylpyruvate dioxygenase-like Other other
74 HSPE1P2 heat shock 10kDa protein 1 pseudogene 2 Other other
75 LINC00158 long intergenic non-protein coding RNA 158 Other other
76 LINC00877 long intergenic non-protein coding RNA 877 Other other
77 LINC00892 long intergenic non-protein coding RNA 892 Other other
78 LINC01132 long intergenic non-protein coding RNA 1132 Other other
79 LINC01281 long intergenic non-protein coding RNA 1281 Other other
80 NAPSB napsin B aspartic peptidase, pseudogene Other other
81 PAICSP4 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase pseudogene 4 Other other
82 PHBP3 prohibitin pseudogene 3 Other other
83 PIK3CD-AS2 PIK3CD antisense RNA 2 Other other
84 RCAN2 regulator of calcineurin 2 Other other
85 RNU5A-8P RNA, U5A small nuclear 8, pseudogene Other other
86 SLC16A9 solute carrier family 16, member 9 Other other

This table contains the 86 genes significantly upregulated by activation of T cells, and significantly downregulated in the presence of BM-MSC or CMPC. It shows the symbol, name, location and the type of the end-product.