Table 4. Developmental guidance molecules mined from adult prothoracic transcriptome.
| Guidance Factor | Trinity ID |
• Predicted Protein Portion • Length |
• Most Similar Drosophila Counterpart • Accession No |
% identity with Drosophila Counterpart |
|---|---|---|---|---|
| Slit | TRINITY_DN152282_c0_g1_i2 | • Full-length • 1,459 AA |
• Slit-F • AGB93549 |
63.5% |
| Robo1 | TRINITY_DN172482_c0_g4_i2 | • Full-length • 1,602 AA |
• Robo1-C • AAM71113 |
40.2% |
| Robo2/3 | TRINITY_DN174950_c3_g2_i1 | • Internal • 1,340 AA |
• Robo3-B • AGB92403 |
40.3% |
| Commisureless | TRINITY_DN156272_c0_g2_i3 | • Internal • 145 AA |
• Comm3-E • AHN58097 |
25.0% |
| Netrin-A | TRINITY_DN160784_c2_g1_i3 | • C-Terminal • 340 AA |
• Netrin-A-C • AHN59713 |
48.3% |
| Frazzled | TRINITY_DN172587_c0_g1_i7 | • Full-length • 1,331 AA |
• Frazzled-A • AAF58493 |
40.7% |
| Unc-5 | TRINITY_DN149614_c0_g1_i1 | • Internal • 254 AA |
• Unc-5-B • AHN56248 |
37.1% |
| Dscam | TRINITY_DN173597_c2_g22_i1 | • C-Terminal • 1,251 AA |
• Dscam1-Y • ABI31042 |
66.8% |
| Ephrin | TRINITY_DN159904_c0_g1_i6 | • C-Terminal • 307 AA |
• Ephrin, isoform C • AAN06500 |
36.1% |
| Eph | TRINITY_DN159184_c0_g1_i3 | • Full-Length • 996 AA |
• Eph isoform E • AAN06503 |
59.5% |
| Sema1a | TRINITY_DN169697_c2_g1_i3 | • Internal • 782 AA |
• Sema-1a-G • AGB92801 |
59.5% |
| Sema2a | TRINITY_DN173773_c2_g2_i6 | • Full-Length • 726 AA |
• Sema-2a-E • AAS64837 |
69.4% |
| Sema5 | TRINITY_DN165105_c1_g2_i8 | • Full-Length • 1,057 AA |
• Sema-5c-B • ACZ94701 |
44.4% |
| Plexin A | TRINITY_DN159247_c0_g1_i2 | • Full Length • 1,909 AA |
• Plexin A-A • AAF59394 |
69.9% |
| Plexin B | TRINITY_DN161683_c0_g1_i2 | • Full Length • 1,850 AA |
• Plexin B-B • AFH06760 |
60.1% |
| Off-track | TRINITY_DN160729_c0_g1_i15 | • Full -Length • 538 AA |
• Off-track-A • AAF58596 |
27.2% |
| Guanylyl Cyclase at 76C | TRINITY_DN166112_c0_g1_i2 | • Internal • 1,135 AA |
• Guanylyl Cyclase at 76C-D • AGB94756 |
58.1% |
| Mical | TRINITY_DN175376_c0_g1_i11 | • Full-Length • 2,614 AA |
• Mical-P ALI30552 |
19.2% |
| PKA-R2 | TRINITY_DN165220_c0_g2_i1 | • Full-Length • 382 AA |
• PKA-R2-B • AAM71046 |
64.6% |
| Rac1 | TRINITY_DN170604_c0_g3_i2 | • Full-Length • 192 AA |
• Rac1-B • AGB93942.1 |
94.8% |
| Rho1 | TRINITY_DN165708_c0_g2_i4 | • Full-Length • 192 AA |
• Rho1-A • AAM70944 |
94.3% |
Drosophila melanogaster query proteins used for tblastn searches were: Slit, (AAF58098) Robo 1, Isoform A (AAF46887), Robo 2 Isoform A (AAF51375), Robo 3, Isoform A (AAF51387), Commisureless, Isoform A (AAF49584.1), Netrin-A, Isoform A (AAF48380), Frazzled, Isoform A (AAF58493), Unc-5, Isoform A (AAF58143), Dscam, Isoform AE (ABI31080), Ephrin, Isoform A (AAF59335), Eph receptor tyrosine kinase, isoform A (AAG22122), Sema1a, Isoform A (AAF52696), Sema2a, Isoform A (AAF57989), Sema5c, Isoform A (AAF49966), Plexin A, Isoform A (AAF59394), Plexin B, Isoform A (AAF59374), Off-track, Isoform A (AAF58596), Mical, Isoform A (AAF54478), protein kinase, cAMP-dependent, regulatory subunit type 2, isoform A (AAF58862), Rac1 Isoform A (AAF47469), Rho 1 (AAA67042).