Fig 1. Inflammation affects the behavior of the small and large intestine.

(a) Schematic of GI tract in human and representative locations of tissue resected in ileum (left) and colon (right). Normal tissue should be similar in the two regions, though the ileum has long villi extending into the lumen and the colon can have thicker muscular regions for compacting and moving stool. (b) Endoscope images show unaffected ileum (i) and inflamed ileum (ii) regions and unaffected colon (iii) and inflamed colon (iv) are clearly visible by optical inspection.