Fig 1. Light field microscope system used for 3D phenotypic imaging.
Green and red ray bundles show how different lateral positions in the sample are focused onto different elements into the microlens array. Abbreviations: C–condenser lens; MO–microscope objective; piezo–piezoelectric nosepiece focusing stage; TL–tube lens; sCMOS–scientific CMOS camera. Inset shows (from left to right): A raw light field micrograph of a swimming C. elegans specimen; a perspective (pinhole) view of the object formed by extracting the same pixel from each microlens subimage; a focused view of the worm formed by summing the signal from all pixels within a microlens subimage. Pixels using to create each image are shown in red.