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. 2018 Jul 11;13(7):e0200517. doi: 10.1371/journal.pone.0200517

Table 3. Pre-post differences on the studied variables in the placebo vs experimental conditions.

SMD (90%CI) Chances of being beneficial/trivial/harmful Qualitative inference % of change (experimental vs placebo) P
Biomechanical parameters
Leg stiffness -0.14 (-0.44, 0.17) 4/61/36 Possibly 2.25 vs 4.64 0.310
Physiological parameters
RE 0.36 (-0.5, 1.21) 63/24/13 Unclear 7.07 vs 4.5 0.589
VO2Max 0.04 (-0.87, 0.95) 37/31/32 Unclear 4.41 vs. 3.66 1.000
Av_RER -0.2 (-1.15, 0.74) 50/27/22 Unclear -4.7 vs. -3.6 1.000
TEx (s) 1.18 (-0.14, 2.5) 90/6/4 Likely 8.18 vs 1.6 0.310
Av_HR 0.03 (-0.36, 0.42) 22/64/15 Unclear -0.26 vs. 1.14 0.792
SmO2 0.72 (0.03, 1.41) 91/7/2 Likely 17.8 vs. -2.64 0.167
Psychological parameters
RPE -2.17 (-3.23, -1.1) 100/0/0 Very likely -9.0 vs 20.4 0.016

Standardized mean differences (SMD) with 90% Confidence Intervals (CI) express the magnitude of the difference on the pre-post changes between the experimental and placebo groups. Positive values reflect higher increments on the placebo group after the supplementation period, while negative scores reflect lower increments on the experimental group after the supplementation period. P is the asymptotic significance of the Mann-Whiteny’s U test.

Abbreviations: RE = running economy; VO2Max = maximal oxygen consumption; Av_RER = average respiratory exchange ratio (whole test); TEx = time to exhaustion; Av_HR = average heart rate (whole test); SmO2 = saturation of muscle O2; RPE = rate of perceived exertion