Table 1.

Clinical manifestations of microvascular involvement in scleroderma and systemic lupus erythematosus.

	Scleroderma	Systemic Lupus Erythematosus
Cutaneous manifestations	Nailfold capilaroscopy changes Raynaud’s phenomenon Acrocyanosis	Nailfold capilaroscopy changes Raynaud’s phenomenon Acrocyanosis Livedo reticularis Cutaneous vasculitis
Pulmonary manifestations	Pulmonary arterial hypertension	Pulmonary arterial hypertension Pulmonary vasculitis
Renal manifestations	Scleroderma renal crisis Microalbuminuria with proteinuria Isolated reduced glomerular filtration rate Reduced renal functional reserve	Lupus nephritis Renal vascular lesions including immune complex deposits, lupus vasculopathy, thrombotic microangiopathy, transmural necrotizing vasculitis
Gastrointestinal manifestations	Gastric antral vascular ectasia	Gastric antral vascular ectasia Intestinal vasculitis
Coronary manifestations	SSc related myocardial disease	Coronary microvascular dysfunction of SLE