Table II-a. Metabolites that decreased after glucose challenge (FDR adjusted paired t-test P-value < 0.001).
| Metabolite | Pathway group | Mean change | SD | Fold Change |
|---|---|---|---|---|
| C8 carnitine | Acylcarnitines | -1.45 | 0.95 | 1.20 |
| C14:2 carnitine | Acylcarnitines | -1.15 | 0.53 | 1.13 |
| C12 carnitine | Acylcarnitines | -1.07 | 0.56 | 1.13 |
| C4-OH carnitine | Acylcarnitines | -0.95 | 0.64 | 1.13 |
| C14:1 carnitine | Acylcarnitines | -1.09 | 0.53 | 1.13 |
| C10 carnitine | Acylcarnitines | -1.04 | 0.57 | 1.11 |
| 5-HETE | Fatty acid | -1.00 | 0.96 | 1.10 |
| C6 carnitine | Acylcarnitines | -0.76 | 0.40 | 1.09 |
| C12:1 carnitine | Acylcarnitines | -1.07 | 0.55 | 1.08 |
| C10:2 carnitine | Acylcarnitines | -0.60 | 0.38 | 1.08 |
| C14 carnitine | Acylcarnitines | -0.57 | 0.47 | 1.07 |
| C30:0 DAG | Diacylglycerols | -0.61 | 0.59 | 1.07 |
| Palmitoleic acid | Fatty acid | -1.26 | 0.43 | 1.07 |
| Gamma-Linolenic acid | Fatty acid | -1.18 | 0.47 | 1.06 |
| C32:2 DAG | Diacylglycerols | -0.56 | 0.69 | 1.06 |
| Aspartate | Amino acid | -0.54 | 0.40 | 1.06 |
| Methinonine sulfoxide | Amino acid | -0.44 | 0.56 | 1.06 |
| Glycine | Amino acid | -0.34 | 0.34 | 1.06 |
| Alpha-glycerophosphocholine | Glycerophospholipids | -0.70 | 0.35 | 1.06 |
| Allantoin | Purine | -0.43 | 0.61 | 1.05 |
| Docosapentaenoic acid | Fatty acid | -0.84 | 0.38 | 1.05 |
| C18:2 carnitine | Acylcarnitines | -0.46 | 0.38 | 1.05 |
| Adrenic acid | Fatty acid | -0.79 | 0.34 | 1.05 |
| C9 carnitine | Acylcarnitines | -0.60 | 0.54 | 1.05 |
| Eicosapentaenoic acid | Fatty acid | -0.77 | 0.36 | 1.05 |
| C18:1 carnitine | Acylcarnitines | -0.47 | 0.34 | 1.05 |
| Glutamate | Amino acid | -0.48 | 0.32 | 1.05 |
| Leucine | Amino acid | -0.56 | 0.26 | 1.04 |
| Isoleucine | Amino acid | -0.52 | 0.22 | 1.04 |
| 8.11.14-Eicosatrienoic acid | Fatty acid | -0.67 | 0.30 | 1.04 |
| Methionine | Amino acids | -0.42 | 0.23 | 1.04 |
| Citrulline | Amino acid | -0.38 | 0.20 | 1.04 |
| Serine | Amino acid | -0.37 | 0.22 | 1.04 |
| Linoleic acid | Amino acid | -0.70 | 0.28 | 1.04 |
| Phenylalanine | Amino acid | -0 47 | 0 27 | 1 04 |
| Oleic acid | Fatty acid | -0.67 | 0.26 | 1.03 |
| Thiamine | Amino acids | -0.46 | 0.37 | 1.03 |
| C18:0 LPE | Lysophosphatidyletha | -0.33 | 0.33 | 1.03 |
| Tyrosine | Amino acid | -0.39 | 0.23 | 1.03 |
| Docosahexaenoic acid | Fatty acid | -0.58 | 0.30 | 1.03 |
| C2 carnitine | Acyclarnitines | -0.43 | 0.30 | 1.03 |
| Asparagine | Amino acid | -0.29 | 0.19 | 1.03 |
| Niacinamide | Amino acid | -0.28 | 0.42 | 1.03 |
| Homocysteine | Amino acid | -0.29 | 0.64 | 1.03 |
| C16 carnitine | Acyclarnitines | -0.26 | 0.21 | 1.03 |
| Palmitic acid | Fatty acid | -0.51 | 0.18 | 1.03 |
| Taurine | Biogenic amines | -0.33 | 0.43 | 1.03 |
| Valine | Amino acids | -0.30 | 0.17 | 1.03 |
| Arachidonic acid | Fatty acid | -0.45 | 0.36 | 1.02 |
| C32:1 DAG | Diacylglycerols | -0.29 | 0.21 | 1.02 |
| Hydroxyproline | Amino Acid | -0.25 | 0.18 | 1.02 |
| C16:0 LPE | Lysophosphatidyletha | -0.24 | 0.33 | 1.02 |
| C42:0 TAG | Triacylglycerol | -0.25 | 0.33 | 1.02 |
| Ornithine | Biogenic amines | -0.23 | 0.25 | 1.02 |
| C18:1 LPE | Lysophosphatidyletha | -0.20 | 0.41 | 1.02 |
| Kynurenic acid | Amino Acid | -0.19 | 0.35 | 1.02 |
| Arginine | Amino acid | -0.31 | 0.20 | 1.02 |
| C32:0 DAG | Diacylglycerols | -0.25 | 0.19 | 1.02 |
| C34:0 DAG | Diacylglycerols | -0.23 | 0.17 | 1.02 |
| Myristic acid | Fatty acid | -0.38 | 0.16 | 1.02 |
| Stearic acid | Fatty acid | -0.37 | 0.18 | 1.02 |
| C18:0 LPC | Lysophosphatidylcholi | -0.28 | 0.24 | 1.02 |
| Threonine | Amino acids | -0.19 | 0.15 | 1.02 |
| C34:3 DAG | Diacylglycerols | -0.18 | 0.20 | 1.02 |
| Choline | Amino Acid | -0.22 | 0.24 | 1.02 |
*
Fold change represents mean of log-pre-OGTT/log- post-OGTT value.