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Comparative epithelial lining fluid concentrations for nebulised and tobramycin sheep at two time points, 1 and 6 h post-antibiotic administration
| ELF time points | Nebulised tobramycin | Intravenous tobramycin |
|---|---|---|
| 1 h (mg/l) | 1.94 | 0.19 |
| 6 h (mg/l) | 0.07 | 0.38 |
| AUCELF (mg-h/l) | 5.99 | 1.52 |
| AUCplasma (mg-h/l) | 56.88 | 53.60 |
| AUClung/AUCplasma (mg-h/l) | 0.11 | 0.03 |
ELF epithelial lining fluid; AUC area under the concentration-time curve
