Table 2.
Summary of evolutionary rates of head antigenic sites and stalk-mAb footprints of sH1N1, pH1N1 and H3N2 based on empirical trees.
Virus | Head Antigenic Sites Evolutionary Rate (a/s/y) (95% BCI*) | Stalk mAb Footprint Evolutionary Rate (a/s/y) | Head Antigenic Sites:Stalk mAb Footprint Rate Ratio |
---|---|---|---|
sH1N1 | 9.90 × 10−3 (9.77 × 10−3–1.00 × 10−2) | 9.11 × 10−4 (7.83 × 10−4–1.04 × 10−3) | 10.9 |
pH1N1 | 9.74 × 10−3 (9.54 × 10−3–9.97 × 10−3) | 3.26 × 10−3 (3.02 × 10−3–3.54 × 10−3) | 3.0 |
H3N2 | 1.29 × 10−2 (1.27 × 10−2–1.30 × 10−2) | 2.96 × 10−3 (2.82 × 10−3–3.10 × 10−3) | 4.3 |
*Bayesian Credible Interval.