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. 2018 Jul 11;8:10443. doi: 10.1038/s41598-018-28722-1

Table 4.

Detailed results of univariate analysis for variables of interest.

Variables Males (n = 214596) P Females (n = 214964) P
Case (%) Control (%) Case (%) Control (%)
Urbanization 0.584 0.753
   Rural area 65 (68.4) 152229 (71.0) 65 (72.2) 151941 (70.7)
   Urban area 30 (31.6) 62272 (29.0) 25 (27.8) 62933 (29.3)
Age (year) 0.153 0.001
   18–44 42 (44.2) 117763 (54.9) 31 (34.4) 117894 (54.9)
   45–64 39 (41.1) 68753 (32.1) 42 (46.7) 69026 (32.1)
   65–79 11 (11.6) 24017 (11.2) 16 (17.8) 23721 (11.0)
   > = 80 3 (3.2) 3968 (1.8) 1 (1.1) 4233 (2.0)
Bean product 0.481 0.607
   Never 0 1388 (0.6) 1 (1.1) 1256 (0.6)
   Always 13 (13.7) 40130 (18.7) 19 (21.1) 40552 (18.9)
   Often 43 (45.3) 99663 (46.5) 35 (38.9) 100770 (46.9)
   Occasionally 28 (29.5) 50185 (23.4) 25 (27.8) 50150 (23.3)
   Seldom 11 (11.6) 23135 (10.8) 10 (11.1) 22146 (10.3)
Ethnicity <0.001 <0.001
   Han 90 (94.7) 200253 (93.4) 86 (95.6) 200621 (93.4)
   Other 5 (5.3) 14248 (6.6) 4(4.4) 14253 (6.6)
BMI 0.481 0.123
   18.5–23.9 64 (67.4) 138093 (64.4) 54 (60.0) 144340 (67.2)
   24–27.9 21 (22.1) 58184 (27.1) 26 (28.9) 44780 (20.8)
   >=28 6 (6.3) 8363 (3.9) 6 (6.7) 9367 (4.4)
   <18.5 4 (4.2) 9861 (4.6) 4 (4.4) 16387 (7.6)
Education 0.985 0.923
   Illiterate 18 (18.9) 34381 (16.0) 17 (18.9) 40393 (18.8)
   Primary school 35 (36.8) 82327 (38.4) 37 (41.1) 80597 (37.5)
   Junior high school 30 (31.6) 68337 (31.9) 27 (30.0) 66554 (31.0)
   Senior high school or above 12 (12.7) 29456 (13.7) 9 (10.0) 27330 (12.7)
Occupation 0.981 <0.001
   Unemployed 6 (6.3) 9597 (4.5) 21 (23.3) 22993 (10.7)
   Office worker 1 (1.1) 6276 (2.9) 1 (1.1) 6188 (2.9)
   Manual worker 33 (34.7) 82403 (38.4) 14 (15.6) 65762 (30.6)
   Farmer 23 (24.2) 48460 (22.6) 30 (33.3) 57500 (26.8)
   Retired 6 (6.3) 14777 (6.9) 9 (10.0) 15420 (7.2)
   Students 9 (9.5) 17580 (8.2) 5 (5.6) 17253 (8.0)
   Other 17 (17.9) 35508 (16.5) 10 (11.0) 29758 (13.8)
Meat and product 0.777 0.267
   Never 0 29 (0.001) 0 2523 (1.2)
    Always 44 (46.3) 111523 (52.0) 36 (40.0) 104977 (48.9)
   Often 33 (34.7) 65004 (30.3) 33 (36.7) 65151 (30.3)
   Occasionally 15 (15.8) 29111 (13.6) 14 (15.6) 31609 (14.7)
   Seldom 3 (3.2) 8834 (4.1) 7 (7.8) 10614 (4.9)
Dairy and product 0.212 0.533
    Never 38 (40.0) 92035 (42.9) 30 (33.3) 77457 (36.0)
    Always 22 (23.2) 31533 (14.7) 14 (15.6) 38374 (17.9)
    Often 15 (15.8) 34564 (16.1) 24 (26.7) 41654 (19.4)
   Occasionally 13 (13.7) 35378 (16.5) 15 (16.7) 37593 (17.5)
   Seldom 7 (7.4) 20991 (9.8) 7 (7.8) 19796 (9.2)
Cigarette smoking 0.027 0.569
   No 41(43.2) 116858 (54.5) 2 (2.2) 7080 (3.3)
   Yes 54 (56.8) 97643 (45.5) 88 (97.8) 207794 (96.7)
Alcohol consumption 0.003 <0.001
   No 30 (31.6) 100778 (47.0) 65 (72.2) 188566 (87.8)
   Yes 65(68.4) 113723 (53.0) 25 (27.8) 26308 (12.2)
Living alone 0.004 0.032
   No 2 (2.1) 756 (0.4) 88 (97.8) 214208 (99.7)
   Yes 93 (97.9) 213745 (99.6) 2 (2.2) 666 (0.3)
Carbonate beverages 0.683 0.690
   Never 58 (61.1) 129665 (60.4) 57 (63.3) 124338 (57.9)
    Always 0 2578 (1.2) 1 (1.1) 2188 (1.0)
   Often 15(15.8) 28821 (13.4) 11 (12.2) 29660 (13.8)
   Occasionally 13 (13.7) 26871 (12.5) 13 (14.4) 29093 (13.5)
   Seldom 9(9.5) 26566 (12.4) 8 (8.9) 29595 (13.8)
Coffee 0.626 0.661
   No 88 (92.6) 200608 (93.5) 85 (94.4) 200447 (93.3)
   Yes 7 (7.4) 13893 (6.5) 5 (5.6) 14427 (6.7)
Tea 0.444 0.736
   Never 51 (53.7) 98910 (46.1) 56 (62.2) 137557 (64.0)
    Always 26 (27.4) 68840 (32.1) 15 (16.7) 34585 (16.1)
   Often 6 (6.3) 22790 (10.6) 7 (7.8) 18266 (8.5
   Occasionally 7 (7.4) 14672 (6.8) 5 (5.6) 14242 (6.6)
   Seldom 5 (5.3) 9289 (4.3) 7 (7.8) 10224 (4.8)
House facing the sun 0.05 0.984
   No 3 (3.2) 2314 (1.1) 1 (1.1) 2335 (1.1)
   Yes 92 (96.8) 212187 (98.9) 89 (98.9) 212439 (98.9)
Living circumstance 0.800 0.832
   Single-storey house 41 (43.2) 85619 (39.9) 36 (40.0) 84696 (39.4)
   House <=7 storey 47 (49.5) 113177 (52.8) 46 (51.1) 114358 (53.2)
   House >7 storey 7 (7.4) 15705 (7.3) 8 (8.9) 15820 (7.4)
Calcium or Vitamin D supplement 0.700 0.976
   No 91 (95.8) 203608 (94.9) 84 (93.3) 200715 (93.4)
   Yes 4 (4.2) 10893 (5.1) 6 (6.7) 14159 (6.6)
Average sleep time (hours) per day 0.003 0.001
   ≥7 49 (51.6) 141352 (65.9) 47 (52.2) 76014 (35.4)
   <7 46 (48.4) 73149 (34.1) 43 (47.8) 138860 (64.6)
Previous history of fracture 0.034 <0.001
   No 89 (93.7) 208585 (97.2) 83 (92.2) 211081 (98.2)
   Yes 6 (6.3) 5916 (2.8) 7 (7.8) 3793 (1.8)
Menopause (age, year) <0.001
   <46 1 (1.1) 5366 (2.5)
   46–50 41 (45.6) 57310 (26.7)
   >50 12 (13.3) 19301 (9.0)
Pre-menopausal 36 (40.0) 132897 (61.8)
Children to give birth <0.001
   No 9 (10.0) 33559 (15.6)
   1 18 (20.0) 82164 (38.2)
   2 47 (52.2) 68588 (31.9)
   3 13 (14.4) 23874 (11.1)
   ≥4 3 (3.3) 6689 (3.1)