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. 2018 Jul 5;9:552. doi: 10.3389/fneur.2018.00552

Table 1.

Steady-state kinetic constants of NQO1 with KL1333, CoQ10, and Idebenone.

NADH oxidation Cytochrome c reduction
KL1333 CoQ10 Idebenone KL1333 CoQ10 Idebenone
Km (μM) 0.27 –* 2.13 0.79 –* 1.76
Vmax (μmol/mg/min) 63.9 –* 38.3 312.4 –* 68.1
*

No enzymatic activity above the background level could be detected for CoQ10; thus, the steady-state kinetics could not be calculated.