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. 2018 Jul 5;12:182. doi: 10.3389/fncel.2018.00182

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Copyright © 2018 Cui, Perez and Venance.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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10 pairings-tLTP is NMDAR-independent. 10 pairings-tLTP is NMDAR-independent. Summary of tLTP induced by 10 pre-post pairings with DL-2-amino-5-phosphono-pentanoic acid (D-AP5; 50 μM; n = 8 cells from 4 rats; Δt_STDP = +10 ± 1 ms). Inhibition of NMDAR with D-AP5 did not prevent the induction of tLTP. Representative traces are the average of 15 excitatory postsynaptic currents (EPSCs) during baseline (black traces) and 50 min after STDP protocol (gray traces). Error bars represent SD. *p < 0.05.