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. 2018 Jul 11;12:443–452. doi: 10.1016/j.omtn.2018.06.001

Figure 4.

Figure 4

Development of Body Weight during the Course of the Experiment

Intact rats and rats treated with E2 directly after ovariectomy showed increased body weight in the context of normal growth. Rats that underwent ovariectomy showed the typical pronounced weight increase. Rats treated with E2 5 weeks after ovariectomy (E2 TG) showed a reduction in weight in the context of E2 treatment. Treatment with virus-like particles had no effect on body weight.