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. Author manuscript; available in PMC: 2019 Jan 2.
Published in final edited form as: Anal Chem. 2017 Nov 7;90(1):19–39. doi: 10.1021/acs.analchem.7b04251

Figure 2.

Figure 2

Common instrumental configurations for surface plasmon resonance. (A) Spectroscopic SPR setup in the Kretschmann configuration, with various component options provided. (B) In SPR imaging, interactions with a patterned plasmonic array are visualized and monitored for changes in reflected light intensity, indicative of molecular binding. (C) SPR microscopy utilizes a high numerical aperture objective to guide incident light toward the gold film at a high angle of incidence. (D) Single mode fiber SPR setup, in which an area of optical fiber cladding is removed and a gold film is deposited.