Table 1.
Association studies of MIR137 rs1625579 polymorphism with risk of schizophrenia.
| Source | Population | Schizophrenia patients | Healthy controls | P-value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Genotype frequencies (%) | N | Genotype frequencies (%) | |||||||
| T/T | G/T | G/G | T/T | G/T | G/G | |||||
| Sun et al. (14) | China | 589 | 86.9 | 12.2 | 0.9 | 622 | 86.8 | 12.7 | 0.5 | p > 0.05 |
| Kuswanto et al. (8) | Singapore | 84 | 89.2 | 10.8 | 63 | 88.9 | 11.1 | p > 0.05 | ||
| Yuan et al. (15) | China | 506 | 87.9 | 11.7 | 0.4 | 522 | 89.6 | 10.4 | 0 | p > 0.05 |
| Wang et al. (16) | China | 300 | 89.7 | 10.3 | 0 | 300 | 88.3 | 11.7 | 0 | p > 0.05 |
| Guan et al. (10) | China | 1429 | 77.7 | 20.8 | 1.5 | 1570 | 74 | 23.6 | 2.4 | p = 0.023 |
| Van Erp et al. (11) | US | 48 | 81.25 | 18.75 | 0 | 63 | 73.02 | 23.81 | 3.17 | p > 0.05 |
| Hommers et al. (5) | GWAS, 2014 | Caucasians n (patients) = 33.332 n (controls) = 27.888 |
p < 0.05 | |||||||
| GWAS, 2013 | Sweden samples: n (patients) = 5.001, n (controls) = 6.243; Repeated study 1 (Caucasians): n (patients) = 8.832, n (controls) = 12.067; Repeated study 2 (Caucasians): n (patients) = 7.413, n (controls) = 19.762 |
p < 0.05 | ||||||||
| GWAS, 2011 | Caucasians n (patients) = 9.394 n (controls) = 12.462 Repeated study n (patients) = 8.432 n (controls) = 21.397 |
p < 0.05 | ||||||||
GWAS, genome wide association study. Bold values indicate the mean statistical significance or % value.