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Effects of ActRIIB.Fc or placebo on myocardial protein content of calcium-handling proteins evaluated by western blot. Bars represent means; error bars are SEM of averaged duplicate measurements for each animal (n = 5 for ActRIIB.Fc; n = 6 for control). a.u. = arbitrary units; PhLB, phospholamban; PKA, protein kinase A; SERCA1, sarcoplasmic calcium ATPase in fast-twitching cardiac myofiber; SERCA2, sarcoplasmic calcium ATPase in slow-twitching cardiac myofiber.
