Table III.
Clinical and imaging findings depending on tissue type according to OCT imaging
| Parameter | FIB-0 (n = 16) Mean ± SD | FIB-1 (n = 27) Mean ± SD | P-value | LRP-0 (n = 28) Mean ± SD | LRP-1 (n = 15) Mean ± SD | P-value |
|---|---|---|---|---|---|---|
| EEM volume [mm] | 123.4 ±53.3 | 124.3 ±57.7 | 0.96 | 115.1 ±55.8 | 140.6 ±52.7 | 0.15 |
| Lumen volume [mm] | 92.9 ±40.4 | 90.9 ±44.8 | 0.71 | 85.2 ±43.2 | 103.7 ±40.5 | 0.09 |
| Min. av. lumen diameter [mm] | 3.1 ±0.6 | 3.0 ±0.4 | 0.56 | 3.0 ±0.4 | 3.1 ±0.5 | 0.40 |
| Min. lumen area [mm2] | 7.8 ±2.8 | 7.4 ±2.1 | 0.95 | 7.3 ±2.1 | 8.0 ±2.7 | 0.62 |
| Min. lumen diameter [mm] | 2.9 ±0.6 | 2.8 ±0.4 | 0.45 | 2.8 ±0.4 | 2.9 ±0.5 | 0.20 |
| Plaque volume [mm] | 30.4 ±14.2 | 33.3 ±14.5 | 0.58 | 29.8 ±14.0 | 36.8 ±14.2 | 0.13 |
| Stenosis EEM [%] | 14.5 ±2.5 | 15.4 ±2.3 | 0.26 | 15.1 ±2.3 | 15.0 ±2.7 | 0.93 |
| Stenosis length [mm] | 10.5 ±3.9 | 10.8 ±3.9 | 0.76 | 10.1 ±3.6 | 11.8 ±4.1 | 0.17 |
| Stenosis reference (%) | 3.1 ±6.5 | 2.9 ±3.6 | 0.19 | 2.3 ±3.6 | 4.3 ±6.5 | 0.42 |
| Total lumen perimeter [mm2] | 109.8 ±41.1 | 111.5 ±43.8 | 0.90 | 103.6 ±41.6 | 124.5 ±41.6 | 0.13 |
| Age [years] | 70.4 ±5.5 | 69.3 ±8.4 | 0.65 | 68.7 ±6.4 | 71.5 ±8.7 | 0.25 |
| Body surface area [m2] | 1.9 ±0.2 | 2.0 ±0.1 | 0.014 | 2.0 ±0.2 | 2.0 ±0.2 | 0.68 |
| Body mass index [kg/m2] | 28.0 ±2.8 | 29.6 ±3.4 | 0.16 | 28.9 ±3.8 | 29.0 ±2.3 | 0.98 |
| LVEF (%) | 49.9 ±8.9 | 46.3 ±11.6 | 0.36 | 46.7 ±11.5 | 49.3 ±9.2 | 0.64 |
| Troponin before [ng/l] | 0.4 ±0.5 | 0.2 ±0.4 | 0.22 | 0.2 ±0.4 | 0.4 ±0.5 | 0.29 |
| Troponin after [ng/l] | 0.4 ±0.5 | 0.2 ±0.4 | 0.22 | 0.2 ±0.4 | 0.4 ±0.5 | 0.29 |
| HGB [mg/dl] | 15.0 ±7.3 | 15.9 ±7.1 | 0.71 | 15.9 ±7.1 | 15.0 ±7.1 | 0.69 |
| WBC [× 103/μl] | 7.1 ±1.8 | 6.9 ±1.6 | 0.54 | 6.9 ±1.4 | 7.1 ±2.0 | 0.97 |
| PLT [× 103/μl] | 221.1 ±65.8 | 189.7 ±40.9 | 0.19 | 182.3 ±31.9 | 231.9 ±65.5 | 0.008 |
| TCH [mg/dl] | 168.6 ±44.4 | 143.3 ±52.2 | 0.08 | 147.7 ±52.2 | 160.4 ±47.9 | 0.76 |
| TG [mg/dl] | 164.4 ±33.1 | 116.0 ±61.0 | 0.013 | 134.8 ±60.4 | 131.2 ±53.3 | 0.86 |
| LDL [mg/dl] | 101.2 ±37.2 | 85.1 ±34.3 | 0.05 | 88.7 ±33.0 | 94.5 ±41.3 | 0.67 |
| HDL [mg/dl] | 34.8 ±9.1 | 43.2 ±14.7 | 0.06 | 40.5 ±14.7 | 39.8 ±11.5 | 0.81 |
| Creatinine [mg/dl] | 1.0 ±0.4 | 1.1 ±0.4 | 0.028 | 1.1 ±0.3 | 1.0 ±0.3 | 0.13 |
| GFR [ml/min/1.73 m2] | 72.4 ±17.9 | 67.3 ±24.7 | 0.77 | 66.8 ±24.6 | 72.9 ±18.7 | 0.50 |
| Male, n (%) | 9 (56) | 26 (96) | 0.004 | 25 (89) | 10 (67) | 0.16 |
| Diabetes, n (%) | 10 (63) | 12 (44) | 0.41 | 14 (50) | 8 (53) | 0.91 |
| Hypertension, n (%) | 16 (100) | 21 (78) | 0.12 | 22 (79) | 15 (100) | 0.14 |
| Current smoking, n (%) | 4 (25) | 0 (0) | 0.029 | 0 (0) | 4 (27) | 0.020 |
FIB-0/1 – fibrotic tissue absent/present, LRP-0/1 – lipid-rich plaque absent/present, EEM – external elastic membrane, min. – minimal, av. – average, LVEF – left ventricular ejection fraction, HGB – hemoglobin, WBC – white blood cells, PLT – platelets, TG – triglyceride, TCH – total cholesterol, LDL – low-density lipoprotein cholesterol, HDL – high-density lipoprotein cholesterol, GFR – glomerular filtration rate; insignificant p-values were rounded up to two decimal places, significant p-values were rounded up to three decimal places.