Table 2.
Weekly warfarin requirements stratified by body mass index.
| Statistical analysis | Therapeutic upon admission |
Newly initiated, therapeutic at discharge |
||||||
|---|---|---|---|---|---|---|---|---|
| Underweight (n = 26) |
Normal/overweight (n = 200) |
Obese (n = 200) |
Morbidly obese (n = 159) |
Underweight (n = 8) |
Normal/overweight (n = 87) |
Obese (n = 67) |
Morbidly obese (n = 29) |
|
| Minimum (mg) | 6 | 3.5 | 6 | 7 | 5.25 | 15.75 | 17.5 | 15.4 |
| Maximum | 59 | 105 | 160 | 140 | 44.2 | 84.58 | 74.38 | 80.5 |
| Mean* | 25.6 | 28.8 | 32.4 | 41.5 | 24.4 | 34.89 | 36.49 | 41.01 |
| Mean adjusted for age$ | 27.6 | 31.3 | 32 | 38.4 | 26.5 | 35.7 | 36 | 39.1 |
| Median$ | 15.75 | 28 | 29 | 35.5 | 24.34 | 32.85 | 33 | 37.69 |
| Mode | 14 | 35 | 35 | 35 | – | 28 | 28 | 46.2 |
| Standard deviation | 18.63 | 15.47 | 18.57 | 18.61 | 13.52 | 13 | 13 | 18.13 |
| Variance | 347 | 239 | 344.7 | 346.3 | 182.67 | 168.93 | 169.05 | 328.59 |
*
p Value < 0.05 in both cohorts.
$
p Value < 0.05 in cohort A.