Figure 1.
PFT-α increases the number of adult SVZ neurospheres (a) and decreases the size of individual neurosphere (b). (c) representative image of neurospheres under different treatment condition. (d) PFT-α increases the number of SGZ neurospheres (d). There is no difference in the neurosphere size for the concentration of PFT-α tested. Mean+ SEM. *, p < 0.05 and **, p < 0.01 compared with control, ANOVA. N = 6–8 wells each condition. ANOVA: analysis of variance; DMSO: dimethyl sulfoxide; NSC: neural stem cell; PFT-α: pifithrin-α; SEM: standard error of the mean; SGZ: subgranular zone; SVZ: subventricular zone.