TABLE 2.
LIST OF THE 68 SC ADIPOSE TISSUE TRANSCRIPTS IN THE UPPER TERTILE OF MEAN EXPRESSION LEVEL AND TOP 2 PERCENTILE OF THE COEFFICIENT OF VARIATION
| Probeset | Symbol | Description | Cytogen. Band | Accession | % CV |
|---|---|---|---|---|---|
| 212657_s_at | IL1RN | Interleukin 1 receptor antagonis | 2q14.2 | U65590 | 121.4 |
| 209875_s_at | SPP1 | Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 4q21-q25 | M83248 | 111.9 |
| 209395_at | CHI3L1 | Chitinase 3-like 1 (cartilage glycoprotein-39) | 1q32.1 | M80927 | 107.9 |
| 203936_s_at | MMP9 | Matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) | 20q11.2-q13.1 | NM_004994 | 92.0 |
| 208691_at | TFRC | Transferrin receptor (p90, CD71) | 3q29 | BC001188 | 79.9 |
| 207332_s_at | TFRC | Transferrin receptor (p90, CD71) | 3q29 | NM_003234 | 66.3 |
| 201952_at | ALCAM | Activated leucocyte cell adhesion molecule | 3q13.1 | AA156721 | 78.8 |
| 201422_at | IFI30 | Interferon, gamma-inducible protein 30 | 19p13.1 | NM_006332 | 75.5 |
| 201850_at | CAPG | Capping protein (actin filament), gelsolin-like | 2p11.2 | NM_001747 | 71.1 |
| 201847_at | LIPA | Lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | 10q23.2-q23.3 | NM_000235 | 64.2 |
| 201720_s_at | LAPTM5 | Lysosomal-associated multispanning membrane protein 5 | 1p34 | AI589086 | 62.6 |
| 201721_s_at | LAPTM5 | Lysosomal-associated multispanning membrane protein 5 | 1p34 | NM_006762 | 60.7 |
| 203523_at | LSP1 | Lymphocyte-specific protein 1 | 11p15.5 | NM_002339 | 62.6 |
| 213274_s_at | CTSB | Cathepsin B | 8p22 | AA020826 | 61.9 |
| 200838_at | CTSB | Cathepsin B | 8p22 | NM_001908 | 57.5 |
| 200839_s_at | CTSB | Cathepsin B | 8p22 | NM_001908 | 44.9 |
| 213275_x_at | CTSB | Cathepsin B | 8p22 | W47179 | 38.9 |
| 219454_at | EGFL6 | EGF-like-domain, multiple 6 | Xp22 | NM_015507 | 60.8 |
| 202803_s_at | ITGB2 | Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 21q22.3 | NM_000211 | 59.2 |
| 202902_s_at | CTSS | Cathepsin S | 1q21 | NM_004079 | 58.2 |
| 203337_x_at | ITGB1BP1 | Integrin beta 1 binding protein 1 | 2p25.2 | NM_004763 | 55.4 |
| 212737_at | GM2A | GM2 ganglioside activator | 5q31.3-q33.1 | AL513583 | 52.5 |
| 209122_at | ADFP | Adipose differentiation-related protein | 9p22.1 | BC005127 | 51.3 |
| 208607_s_at | SAA2 | Serum amyloid A2 | 11p15.1-pl4 | NM_030754 | 51.2 |
| 205516_x_at | CIZ1 | CDKN1A interacting zinc finger protein 1 | 9q34.1 | NM_012127 | 49.7 |
| 202546_at | VAMP8 | Vesicle-associated membrane protein 8 (endobrevin) | 2p12-p11.2 | NM_003761 | 49.6 |
| 200766_at | CTSD | Cathepsin D (lysosomal aspartyl protease) | 11p15.5 | NM_001909 | 48.4 |
| 202409_at | IGF2 | Insulin-like growth factor 2 (somatomedin A) | 11p15.5 | X07868 | 48.1 |
| 204122_at | TYROBP | TYRO protein tyrosine kinase binding protein | 19q13.1 | NM_003332 | 46.8 |
| 218520_at | TBK1 | TANK-binding kinase 1 | 12q14.1 | NM_013254 | 46.6 |
| 214456_x_at | SAA1 | Serum amyloid A1 | 11p15.1 | M23699 | 46.6 |
| 204232_at | FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 1q23 | NM_004106 | 46.3 |
| 221651_x_at | IGKC | Immunoglobulin kappa constant | 2p12 | BC005332 | 46.2 |
| 201141_at | GPNMB | Glycoprotein (transmembrane) nmb | 7p15 | NM_002510 | 46.0 |
| 201201_at | CSTB | Cystatin B (stefin B) | 21q22.3 | NM_000100 | 45.9 |
| 221269_s_at | SH3BGRL3 | SH3 domain binding glutamic acid-rich protein like 3 | 1p35-p34.3 | NM_031286 | 45.3 |
| 203649_s_at | PLA2G2A | Phospholipase A2, group IIA (platelets, synovial fluid) | 1p35 | NM_000300 | 42.9 |
| 218540_at | THTPA | Thiamine triphosphatase | 14q11.2 | NM_024328 | 42.1 |
| 209659_s_at | CDC16 | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 13q34 | AF164598 | 41.9 |
| 20083l_s_at | SCD | Stearoyl-CoA desaturase (delta-9-desaturase) | 10q23-q24 | AA678241 | 41.6 |
| 213553_x_at | APOC1 | Apolipoprotein C-I | 19q13.2 | W79394 | 41.4 |
| 213101_s_at | ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 2q14.1 | Z78330 | 40.0 |
| 202605_at | GUSB | Glucuronidase, beta | 7q21.11 | NM_000181 | 39.7 |
| 201050_at | PLD3 | Phospholipase D family, member 3 | 19q13.2 | NM_012268 | 39.6 |
| 202399_s_at | AP3S2 | Adaptor-related protein complex 3, sigma 2 subunit | 15q26.1 | NM_005829 | 39.5 |
| 202404_s_at | COL1A2 | Collagen, type I, alpha 2 | 7q22.1 | NM_000089 | 39.5 |
| 201108_s_at | THBS1 | Thrombospondin 1 | 15q15 | BF055462 | 38.9 |
| 201470_at | GSTO1 | Glutathione-S-transferase omega 1 | 10q25.1 | NM_004832 | 38.8 |
| 201251_at | PKM2 | Pyruvate kinase, muscle | 15q22 | NM_002654 | 38.5 |
| 200078_s_at | ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 1p32.3 | BC005876 | 37.9 |
| 213515_x_at | HBG1 | Hemoglobin, gamma A | 11p15.5 | AI133353 | 37.7 |
| 217118_s_at | C22orf9 | Chromosome 22 open reading frame 9 | 22q13.31 | AK025608 | 37.6 |
| 203382_s_at | APOE | Apolipoprotein E | 19q13.2 | NM_000041 | 37.6 |
| 201944_at | HEXB | Hexosaminidase B (beta polypeptide) | 5q13 | NM_000521 | 37.2 |
| 209390_at | TSC1 | Tuberous sclerosis 1 | 9q34 | AF013168 | 37.0 |
| 203381_s_at | APOE | Apolipoprotein E | 19q13.2 | N33009 | 36.8 |
| 201005_at | CD9 | CD9 molecule | 12p13.3 | NM_001769 | 36.7 |
| 218109_s_at | MFSD1 | Major facilitator superfamily domain containing 1 | 3q25.33 | NM_022736 | 36.5 |
| 203920_at | NR1H3 | Nuclear receptor subfamily 1, group H, member 3 | 11p11.2 | NM_005693 | 36.4 |
| 207168_s_at | H2AFY | H2A histone family, member Y | 5q31.3-q32 | NM_004893 | 36.4 |
| 208998_at | UCP2 | Uncoupling protein 2 (mitochondrial, proton carrier) | 11q13.4 | U94592 | 35.7 |
| 207977_s_at | DPT | Dermatopontin | 1q12-q23 | NM_001937 | 35.7 |
| 203416_at | CD53 | CD53 molecule | 1p13 | NM_000560 | 35.7 |
| 201954_at | ARPC1B | Actin related protein 2/3 complex, subunit 1B, 41 kDa | 7q22.1 | NM_005720 | 35.6 |
| 201525_at | APOD | Apolipoprotein D | 3q26.2-qter | NM_001647 | 35.4 |
| 209183_s_at | C10orf10 | Chromosome 10 open reading frame 10 | 10q11.21 | AL136653 | 35.0 |
| 202087_s_at | CTSL | Cathepsin L | 9q21-q22 | NM_001912 | 34.9 |
| 217753_s_at | RPS26 | Ribosomal protein S26 | 12q13 | NM_001029 | 34.7 |