TABLE 1.
GENES INVOLVED IN LIPID METABOLISM AND HOMEOSTASIS
| Gene Symbol | GenBank | Fold Change | p-Value | Gene Ontology Biological Process |
|---|---|---|---|---|
| CHKA | NM_001277 | −1.16 | 0.0024 | lipid metabolic process |
| HMGCS1 | NM_001098272 | −2.16 | 0.0012 | lipid metabolic process |
| SC4MOL | NM_001017369 | −1.93 | 0.0007 | fatty acid metabolic process |
| FDFT1 | NM_004462 | −1.80 | 0.0001 | steroid biosynthetic process |
| HMGCR | NM_000859 | −1.60 | 0.0003 | steroid biosynthetic process |
| DHCR7 | NM_001360 | −1.59 | 0.0048 | blood vessel development |
| DHCR24 | NM_014762 | −1.41 | 0.0029 | steroid biosynthetic process |
| SQLE | NM_003129 | −1.55 | 0.0073 | metabolic process |
| IDI1 | NM_004509 | −1.48 | 0.0030 | steroid biosynthetic process |
| CYP51A1 | NM_00786 | −1.45 | 0.0056 | steroid biosynthetic process |
| FDPS | NM_002004 | −1.44 | 0.0036 | steriod biosynthetic process |
| LSS | NM_001001438 | −1.44 | 0.0105 | steriod biosynthetic process |
| SC5DL | NM_001024956 | −1.43 | 0.0018 | lipid metabolic process |
| MVD | NM_002461 | −1.34 | 0.0045 | steroid biosynthetic process |
| NSDHL | NM_001129765 | −1.25 | 0.0225 | hair follicle development |
| MPO | NM_000250 | −1.12 | 0.0132 | antiapoptosis |
| EHHADH | NM_001966 | 1.11 | 0.0195 | lipid metabolic process |
| ABCG4 | NM_004827 | −1.19 | 0.0350 | transport |
| ABCG1 | NM_004915 | 2.08 | 0.0002 | transport/lipid |
| BACE1 | NM_012104 | −1.13 | 0.0058 | proteolysis |
| CHRND | NM_000751 | −1.15 | 0.0172 | transport |
| GABRE | NM_004961 | −1.13 | 0.0387 | transport |
| LDLR | NM_000527 | −1.25 | 0.0117 | protein amino acid O-linked glycosylation |
| APOA4 | NM_000482 | −1.15 | 0.0408 | innate immune response in mucosa |
| APOE | NM_00041 | −1.11 | 0.0270 | response to reactive oxygen species |
| HSD17812 | NM_016142 | −1.13 | 0.0127 | steroid biosynthetic process |
| HSD1787 | NM_016371 | −1.58 | 0.0006 | steroid biosynthetic process |
| STXBP3 | NM_007269 | 1.24 | 0.0209 | transport |
| INSIG1 | NM_005542 | −1.57 | 0.0031 | lipid metabolic process |
| DHCR24 | NM_014762 | −1.14 | 0.0029 | steroid biosynthetic process |
| C14orfl | NM_007176 | −1.33 | 0.0028 | steroid biosynthetic process |
| FADS2 | NM_004265 | −1.30 | 0.0305 | lipid metabolic process |
| BDH2 | NM_020139 | −1.17 | 0.0007 | fatty acid β-oxidation |
| TM7SF2 | NM_003273 | −1.16 | 0.0425 | steroid biosynthetic process |
| CEL | NM_001807 | −1.15 | 0.0051 | lipid metabolic process |
| ACOT7 | NM_007274 | −1.11 | 0.0291 | lipid metabolic process |
| ELOVL5 | NM_021814 | −1.10 | 0.0140 | fatty acid biosynthetic process |
| AGPAT2 | NM_001012727 | −1.10 | 0.0009 | phospholipid metabolic process |
| ABCA4 | NM_000350 | 1.11 | 0.0344 | phospholipid transfer to membrane |
| PLCL1 | NM_001114661 | 1.12 | 0.0196 | lipid metabolic process |