TABLE 2.
GENES INVOLVED IN CELL CYCLE REGULATION
Gene Symbol | GenBank | Fold Change | p-Value | Gene Ontology Biological Process | Pathway |
---|---|---|---|---|---|
CHKA | NM_001277 | −1.16 | 0.0024 | lipid metabolic process | acetylcholine synthesis |
CASP1 | NM_001223 | −1.11 | 0.0373 | proteolysis | apoptosis |
MYC | NM_002467 | −1.20 | 0.0351 | transcription | apoptosis/G1 to S cell cycle |
CCNA2 | NM_001237 | −1.18 | 0.0112 | cell cycle | cell cycle |
CCNB2 | NM_004701 | −1.18 | 0.0152 | cell cycle | cell cycle |
PLK1 | NM_005030 | −1.20 | 0.0097 | protein amino acid phosphorylation | cell cycle |
CDC20 | NM_001255 | −1.19 | 0.0230 | ubiquitin-dependent protein catabolic process | cell cycle |
DBF4 | NM_006716 | −1.19 | 0.0337 | G1/S transition of mitotic cell cycle | cell cycle/DNA replication |
CDKN2A | NM_000077 | 1.10 | 0.0144 | cell cycle checkpoint | G1 to S cell cycle |
RB1 | NM_000321 | 1.16 | 0.0229 | cell cycle checkpoint G1 | G1 to S cell cycle |
TNXB | NM_019105 | −1.19 | 0.0123 | transcription | G1 to S cell cycle |
TNXA | NM_019105 | −1.17 | 0.0039 | transcription | G1 to S cell cycle |
INHBA | NM_002192 | −1.22 | 0.0491 | G1/S transition of mitotic cell cycle | TGF-β signaling |
ENG | NM_000118 | −1.22 | 0.0083 | transport | TGF-β signaling |
MPO | NM_000250 | −1.12 | 0.0132 | antiapoptosis | |
C17orf88 | XR_017759 | −1.21 | 0.0151 | apoptosis | |
DAP | NM_004394 | −1.10 | 0.0234 | apoptosis | |
GAS2 | NM_005256 | −1.11 | 0.0131 | apoptosis | |
TNFRSF14 | NM_003820 | −1.11 | 0.0243 | apoptosis | |
MOAP1 | NM_022151 | 1.12 | 0.0328 | apoptosis | |
CETN2 | NM_004344 | −1.17 | 0.0192 | cell cycle | |
NCAPG | NM_022346 | −1.16 | 0.0182 | cell cycle | |
RBBP4 | NM_005610 | −1.13 | 0.0004 | DNA replication | |
RAD17 | NM_002873 | 1.11 | 0.0205 | DNA replication checkpoint | |
GSPT1 | NM_001130006 | −1.21 | 0.0208 | G1/S transition of mitotic cell cycle | |
RCC1 | NM_001048194 | −1.25 | 0.0228 | G1/S transition of mitotic cell cycle | |
MPHOSPH6 | NM_005792 | −1.11 | 0.0104 | M phase of mitotic cell cycle | |
NUSAP1 | NM_001129897 | −1.25 | 0.0140 | mitotic sister chromatid segretation | |
BCL71 | NM_001024808 | −1.20 | 0.0348 | negative regulation of transcription | |
CDKN3 | NM_001130851 | −1.23 | 0.0077 | regulation of cyclin-dependent protein kinase activity | |
CKS2 | NM_001827 | −1.14 | 0.0134 | regulation of cyclin-dependent protein kinase activity | |
RBL2 (p130) | NM_005611 | 1.19 | 0.0053 | transcription |