Table 6.
Issues on Interests and Limits of Soluble Biomarkers for Managing Retreatment with Viscosupplementation | Level of Consensus | Agreement |
|
---|---|---|---|
Agree | Disagree | ||
The effect of viscosupplementation on cartilage metabolism is a valuable outcome in the follow-up of OA patient | Strongly in favor | 8 | 2 |
Soluble biomarkers are predictive of the response to viscosupplementation | Moderately against | 3 | 7 |
Soluble biomarkers can be used as indicator of HA reinjection | Strongly against | 2 | 8 |
Soluble biomarkers are good tools, useful for monitoring the effects of VS on cartilage metabolism in daily practice | Strongly against | 2 | 8 |
Soluble biomarkers are good tools, useful for monitoring the effects of VS on cartilage metabolism in clinical trials | Strongly in favor | 9 | 1 |
VS = viscosupplementation; OA = osteoarthritis; HA = hyaluronic acid.