Table 1.

Navajo demographic and clinical characteristics by gender.

Variable	Female (n = 145)	Male (n = 107)	Value above, below median for AS	Value above, below median for U
Age (years)	55.5 ± 14	55.1 ± 14.7	54.0 ± 14.0, 56.2 ± 14.1	55.7 ± 14.1, 54.6 ± 14.4
BMI, kg/m2	31.2 (27.7–34.9)	28.2 (26.1–31.5)	29.0 ± 5.5, 29.0 ± 5.0	28.7 ± 5.4, 29.3 ± 5.1
Total Cholesterol, mg/dL	182.5 (163.3–201.8)	182 (159.5–204.5)	184.1 ± 36.8, 186.9 ± 33.5	186.6 ± 36.2, 184.5 ± 34.6
LDL, mg/dL	105 (90.3–123.8)	104 (88–122)	109.0 ± 31.0, 107.1 ± 32.4	113.0 ± 28.9, 103.1 ± 33.2
HDL, mg/dL	47.5 (39–57)	42 (34–49.5)	47.6 ± 13.4, 47.8 ± 18.2	47.6 ± 14.0, 47.8 ± 17.8
Triglycerides, mg/dL	177 (127.5–247.3)	191 (125–261.5)	204.9 ± 141.7, 224.5 ± 136.8	198.6 ± 114.0, 231.0 ± 166.4
Systolic BP (mmHg)	126 (114–142)	132 (121.5–145.5)	128.8 ± 20.1, 134.0 ± 20.3	133.5 ± 21.0, 129.8 ± 19.6
Diastolic BP (mmHg)	76 (70–85)	81 (73–88.5)	77.6 ± 12.9, 80.6 ± 11.3	79.2 ± 13.0, 79.2 ± 11.3
Glucose (non-fasting), mg/dL	90 (77–122.8)	92 (79–120)	120.0 ± 75.4, 129.1 ± 89.2	119.9 ± 78.2, 129.3 ± 87.1
Median HbA1c, %	6.3 (5.9–7.3)	6 (5.6–6.9)	6.83 ± 1.97, 7.08 ± 2.10	6.74 ± 1.76, 7.17 ± 2.26
% Normal (≤ 5.6%)	7.7	26.4
% Pre-diabetes (5.7–6.4%)	50.3	39.6
% Diabetes (≥ 6.5%)	42	34
Oxidized LDL, U/L	45.7 (36.7–57)	48.7 (36.7–57.2)	48.8 ± 18.43, 48.1 ± 15.2	49.7 ± 18.3, 47.3 ± 15.5
CRP, mg/L	2.5 (0.9–5.2)	1.8 (0.9–4.2)	3.59 ± 3.83, 4.96 ± 12.69	4.02 ± 11.8, 4.54 ± 6.69
CRP > 3.0 mg/L, %	44	32
Mean Water Arsenic, ppb (10–90%ile)	2.48 (1.00–6.00)	4.80 (1.00–4.85)
Mean Water Uranium, ppb (10–90%ile)	5.35 (0.38–13.23)	6.04 (0.38–13.30)

Data are presented as median (IQR) or %; age was reported as mean (SD). BMI: body mass index; LDL: low-density lipoprotein; HDL: high-density lipoprotein; BP: blood pressure; HbA1c: glycated hemoglobin; CRP: C-reactive protein.