Table 2.
Residual parasite densities (estimated by ultrasensitive PCR quantitation) by treatment arm presented as a percentage relative to baseline density
| Time point | AL3 | AL5 | p value# | ||
|---|---|---|---|---|---|
| n/N | (Median; min–max) | n/N | (Median, min–max) | ||
| At 3 days | 61/75 | 0.39 (0–2.72.17) | 60/72 | 0.72 (0–133.48) | 0.42 |
| At 5 days | 10/20 | 0.01 (0–82.13) | 8/18 | 0 (0–0.40) | 0.50 |
| At 7 days | 41/74 | 0.003 (0–7.00) | 40/71 | 0.003 (0–6.72) | 0.72 |
| At 14 days | 15/54 | 0 (0–0.04) | 16/55 | 0 (0–0.44) | 0.58 |
| At 21 days | 5/52 | 0 (0–0.01) | 8/53 | 0 (0–0.48) | 0.33 |
N number of patients tested, n number positive
Residual parasite density % calculation = 100 − [{(Parasite density day 0 − Parasite density day x)/Parasite density day 0} × 100]
#Wilcoxon rank-sum (Mann–Whitney) test