Fig. 1.

MiR-155 is upregulated in bone marrow-derived macrophages. a Bone marrow-derived macrophages (BMDMs) from miR-155 knock-out (KO) and wild-type (WT) mice were cultured after 7 days and the purity of BMDMs analyzed by flow cytometry. The BMDMs were double-positive for CD11b and F4/80. b BMDMs from miR-155KO and WT mice were treated with MSU for 4 and 8 h, and miR-155 expression was detected by Taqman real-time qPCR. Results are representative of three independent experiments; n = 3–5 mice per group. **P < 0.01. NS not significant