Table 7.
Associations between ATP2B1 and CACNB2 polymorphisms and high blood pressure by sex (allelic models)
| Boys | OR (95 % CI) |
P value | Girls | OR (95 % CI) |
P value | |||
| HBP | NBP | HBP | NBP | |||||
| N (%) | N (%) | N (%) | N (%) | |||||
| ATP2B1 alleles | ||||||||
| A | 249 (87.1) | 287 (84.4) | 1.00 | 165 (84.4) | 400 (87.8) | 1.00 | ||
| G | 37 (12.9) | 53 (15.6) | 0.80 (0.50 to 1.30) | 0.346 | 23 (15.6) | 78 (12.2) | 0.71 (0.42 to 1.21) | 0.186 |
| CACNB2 alleles | ||||||||
| C | 179 (62.6) | 249 (73.2) | 1.00 | 112 (59.6) | 311 (65.1) | 1.00 | ||
| G | 107 (37.4) | 91 (26.8) | 1.64 (1.15 to 2.33) | 0.004 | 76 (40.4) | 167 (34.9) | 1.26 (0.88 to 1.81) | 0.185 |
ATP2B1, the plasma membrane calcium-transporting ATPase 1 gene; CACNB2, beta-2 subunit of voltage-gated calcium channel; HBP, high blood pressure; NBP, normal blood pressure.
ORs in bold text are statistically significant (p< 0.05).