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. 2018 Jun 30;8(6):e020906. doi: 10.1136/bmjopen-2017-020906

Table 2.

Pre-ICBT and post-ICBT intervention measures for eight donors or donor candidates

Outcome measures Before ICBT After ICBT r (pre-ICBT and post-ICBT) Effect size (Hedges’ g)*
M SD M SD
Health-related quality of life (RAND SF-36)†
Physical HRQoL
 Physical Health Composite Score 54.13 4.7 56.38 4.1 0.82 0.30
 Physical functioning 55.50 4.6 55.38 3.1 0.96 −0.01
 Role limitations—physical health problems 54.13 5.3 55.00 8.9 −0.14 0.15
 Pain 55.63 6.6 57.75 8.1 0.25 0.35
 General health perceptions 51.00 5.2 55.00 3.9 0.94 0.30
Psychological HRQoL
 Mental Health Composite Score 51.25 6.9 54.25 2.8 0.24 0.61
 Emotional well-being 48.88 7.3 50.88 5.9 0.31 0.35
 Role limitations—mental health problems 49.75 8.5 52.63 8.3 −0.20 0.43
 Social functioning 54.63 4.8 53.00 4.2 0.40 −0.39
 Energy 51.25 6.6 57.50 7.0 0.38 1.02
Anxiety and depression (Hospital Anxiety and Depression Scale)‡
 Depression 2.00 1.9 1.88 1.6 0.63 0.06
 Anxiety 4.00 2.7 4.50 3.0 0.05 −0.24
Fatigue (CIS short version)‡
 Fatigue 9.75 6.4 9.63 6.0 0.93 0.01

n=8.

*Effect sizes were presented using negative values indicating a reduction of symptoms.

†Higher scores represent better functioning.

‡Higher scores represent more symptoms.

CIS, Checklist Individual Strength–Fatigue Scale; HRQoL, health-related quality of life; ICBT, internet-based cognitive-behavioural therapy; RAND SF-36, RAND Short Form-36 Health Status Inventory.