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. 2018 Jul 6;8(7):e022960. doi: 10.1136/bmjopen-2018-022960

Table 2.

Univariate and multivariate analyses of overall survival

Variable Univariate analysis Multivariate analysis
HR (95% CI) P values HR (95% CI) P values
Age (per year) 1.02 (1.01 to 1.03) 0.011 1.03 (1.01 to 1.05) 0.006
Gender (female vs male) 0.94 (0.78 to 1.13) 0.501
Hypertension (yes vs no) 0.95 (0.66 to 1.37) 0.774
Diabetes mellitus (yes vs no) 1.27 (0.87 to 1.87) 0.221
CKD (yes vs no) 2.37 (1.43 to 3.94) 0.001 2.13 (1.11 to 4.09) 0.023
History of HF (yes vs no) 1.27 (0.85 to 1.90) 0.244
VHD (yes vs no) 1.50 (0.95 to 2.37) 0.079
CHD (yes vs no) 0.96 (0.67 to 1.37) 0.808
DCM (yes vs no) 0.63 (0.37 to 1.11) 0.114
HCM (yes vs no) 0.70 (0.17 to 2.81) 0.610
HHD (yes vs no) 0.64 (0.16 to 2.60) 0.536
AF (yes vs no) 1.26 (0.87 to 1.84) 0.221
BNP (per 100 pg/mL) 1.01 (1.00 to 1.02) <0.001 1.01 (1.00 to 1.02) 0.034
LVEF (per 1%) 1.00 (0.98 to 1.01) 0.623
IVST (per mm) 1.10 (0.99 to 1.21) 0.066
PWT (per mm) 1.09 (0.99 to 1.19) 0.076
LVDv (per mL) 1.01 (1.00 to 1.02) 0.028 1.00 (0.99 to 1.01) 0.393
LVSv (per mL) 1.01 (1.00 to 1.02) 0.033 1.01 (1.00 to 1.02) 0.006
LAD (per mm) 1.02 (1.01 to 1.04) 0.001 1.03 (1.01 to 1.05) 0.001
AGR (>1.48 vs ≤1.48) 0.54 (0.37 to 0.80) 0.001 0.61 (0.38 to 0.98) 0.040
AGR (reference: first tertile)
AGR second tertile 0.84 (0.55 to 1.28) 0.412 0.82 (0.54 to 1.25) 0.350
AGR third tertile 0.56 (0.36 to 0.89) 0.014 0.62 (0.39 to 0.98) 0.040
AGS (0 vs 1–2) 0.56 (0.37 to 0.84) 0.005 0.81 (0.41 to 1.57) 0.525

AF, atrial fibrillation; AGR, albumin to globulin ratio; AGS, albumin-globulin score; BNP, B-type natriuretic peptide; CHD, coronary heart disease; CKD, chronic kidney disease; DCM, idiopathic dilated cardiomyopathy; HCM, hypertrophic cardiomyopathy; HF, heart failure; HHD, hypertensive heart disease; IVST, interventricular septum thickness; LAD, left atrial dimension; LVDv, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVSv, left ventricular end-systolic volume; PWT, posterior wall thickness; VHD, valvular heart disease.