Fig 1. Oligopainting of the Drosophila genome and the effect of condensin II depletion.

(A) Custom Oligopaint probe libraries were designed to mark the nonrepetitive regions of the Drosophila genome. The extent of chromosome intermixing was calculated and found to increase upon condensin II knockdown. (B) The Oligopaint library was modified to mark 3 regions of 1 arm of chromosome 2. Condensin II knockdown led to an increase in an “open” configuration of the arm.