Fig 4. Regulation of biological processes enriched from convoluted and deconvolved data.

Significant regulation of cellular function is shown for convoluted (conv.) and deconvolved (deconv.) transcript expression microarray data from normal mouse thyroid. Regulation is in response to 90 kBq ¹³¹I after 24 h following i.v. administration. Enriched biological processes were grouped into categories and subcategories of associated cellular function based on Gene Ontology terms. The percentage of scored vs. filtered transcripts is shown as very low <3%, low 3–9%, medium 10–29%, high 30–49%, and very high ≥50%, and colored as very light blue, light blue, blue, dark blue, and very dark blue, respectively. Values in white text show number of scored/filtered transcripts for each category and subcategory. For original results on enrichment analysis for convoluted thyroid tissue, please refer to Langen et al. [16].